Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   D1369_RS39705 Genome accession   NZ_CP031969
Coordinates   8647257..8647928 (+) Length   223 a.a.
NCBI ID   WP_007379596.1    Uniprot ID   B5I8B6
Organism   Streptomyces sp. CC0208     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8642257..8652928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1369_RS39690 - 8642794..8642982 (-) 189 Protein_7805 transposase -
  D1369_RS39695 - 8643622..8645760 (+) 2139 WP_118083029.1 MMPL family transporter -
  D1369_RS39700 - 8645995..8647260 (+) 1266 WP_106433577.1 histidine kinase -
  D1369_RS39705 vraR 8647257..8647928 (+) 672 WP_007379596.1 response regulator transcription factor Regulator
  D1369_RS39710 - 8648097..8648477 (+) 381 WP_007379595.1 AQJ64_40280 family protein -
  D1369_RS39715 - 8648540..8649628 (-) 1089 WP_162951049.1 alcohol dehydrogenase catalytic domain-containing protein -
  D1369_RS39720 - 8649731..8650624 (+) 894 WP_007379592.1 LysR family transcriptional regulator -
  D1369_RS39725 - 8650874..8652204 (+) 1331 Protein_7812 IS1380 family transposase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23512.17 Da        Isoelectric Point: 4.7170

>NTDB_id=273879 D1369_RS39705 WP_007379596.1 8647257..8647928(+) (vraR) [Streptomyces sp. CC0208]
MTIRVLLADDQNLVRTSFAMLVSSAGDMEVVAEAGTGREAVELARSARADLIVMDIRMPDLDGIEATRLIAADEDLAGVK
VLVLTTYETDEHIVEALRAGASGFLVKDIRPAELLDAIRTVAAGESLLSPGPTSRLIARFLLAPNTAPKPALGGPSELSE
RERQVLALVARGLNNAEIADALGLSPLTAKTHVSRIMGKLGARDRAQLVIVAYESGLVIPGTV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=273879 D1369_RS39705 WP_007379596.1 8647257..8647928(+) (vraR) [Streptomyces sp. CC0208]
ATGACCATCCGCGTACTGCTGGCCGACGACCAGAACCTCGTACGGACCTCCTTCGCGATGCTCGTCTCGTCGGCAGGCGA
CATGGAGGTCGTCGCAGAGGCGGGCACCGGGCGGGAGGCCGTGGAGCTGGCCCGGTCGGCGCGGGCCGATCTCATCGTGA
TGGACATCCGCATGCCCGACCTCGACGGGATCGAGGCGACCCGGCTCATCGCCGCCGACGAGGATCTCGCGGGGGTGAAG
GTGCTCGTCCTGACGACGTACGAGACCGACGAGCACATCGTCGAGGCACTGAGGGCCGGGGCGTCCGGCTTCCTCGTGAA
GGACATCAGGCCGGCCGAACTCCTCGACGCCATCCGGACGGTGGCCGCGGGGGAGTCCCTCCTCTCGCCCGGCCCCACCT
CGCGGCTGATCGCCCGCTTTCTGCTCGCGCCGAACACCGCGCCGAAACCCGCGCTGGGCGGGCCGAGCGAGCTGTCCGAA
CGGGAACGGCAGGTGCTCGCGCTGGTCGCGCGCGGTCTCAACAACGCGGAGATCGCCGACGCGTTGGGACTCAGTCCGCT
GACCGCGAAGACCCATGTCAGCCGGATCATGGGCAAGTTGGGGGCGCGGGACCGGGCGCAACTGGTGATCGTGGCGTACG
AGTCGGGGCTTGTGATACCTGGGACTGTCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(5-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B5I8B6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.073

97.758

0.372

Multiple sequence alignment