Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   D1369_RS37035 Genome accession   NZ_CP031969
Coordinates   8076726..8077373 (-) Length   215 a.a.
NCBI ID   WP_007380094.1    Uniprot ID   B5I5B9
Organism   Streptomyces sp. CC0208     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8071726..8082373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1369_RS37020 - 8072538..8073983 (-) 1446 WP_007380097.1 glyceraldehyde-3-phosphate dehydrogenase -
  D1369_RS37025 - 8074060..8075289 (-) 1230 WP_050789669.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
  D1369_RS37030 - 8075379..8076518 (-) 1140 WP_037899009.1 GNAT family N-acetyltransferase -
  D1369_RS37035 vraR 8076726..8077373 (-) 648 WP_007380094.1 response regulator transcription factor Regulator
  D1369_RS37040 - 8077370..8078572 (-) 1203 WP_007380093.1 sensor histidine kinase -
  D1369_RS37045 - 8078733..8079518 (+) 786 WP_007380092.1 class I SAM-dependent methyltransferase -
  D1369_RS37050 - 8080012..8080632 (+) 621 WP_118082874.1 TOPRIM nucleotidyl transferase/hydrolase domain-containing protein -
  D1369_RS37055 - 8080791..8081903 (+) 1113 WP_007380090.1 Gfo/Idh/MocA family oxidoreductase -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 22771.26 Da        Isoelectric Point: 7.3627

>NTDB_id=273872 D1369_RS37035 WP_007380094.1 8076726..8077373(-) (vraR) [Streptomyces sp. CC0208]
MSTLPPSSPVRLLLCDDHAVVRAGLRALLSSADGIDVVGEAATGEEALAMAAHLNPDVVLMDLQLEGGMDGVTATRRLTA
RGERGPRVLVLTMFDTDADITRAVEAGAIGYLLKAEQPEELFSAIRDAASGRGALSAPVADRLLTRLRSPRPALSAREHE
ILAQLARGLGNREIARALFISEATVKTHLGRIYGKLGVETRAGAVAVAKERRLLP

Nucleotide


Download         Length: 648 bp        

>NTDB_id=273872 D1369_RS37035 WP_007380094.1 8076726..8077373(-) (vraR) [Streptomyces sp. CC0208]
GTGAGCACGTTGCCGCCCTCCTCCCCCGTACGGCTCCTGCTCTGCGACGACCATGCCGTCGTACGCGCCGGGCTGCGCGC
CCTGCTCTCCAGCGCGGACGGCATCGACGTGGTCGGGGAGGCCGCGACCGGGGAGGAGGCGCTCGCCATGGCGGCGCACC
TGAACCCCGACGTCGTACTGATGGATCTTCAACTCGAAGGCGGCATGGACGGGGTGACCGCCACCCGGCGGCTGACCGCC
CGCGGCGAGCGGGGCCCTCGGGTGCTGGTGCTCACCATGTTCGACACCGACGCCGACATCACCCGCGCCGTCGAGGCGGG
CGCCATCGGTTATCTCCTCAAGGCGGAACAGCCCGAGGAGCTGTTCTCCGCCATCCGTGACGCGGCGTCGGGCCGCGGCG
CGCTGTCCGCGCCGGTGGCCGACCGGCTGCTGACCCGGCTGCGCAGCCCGCGCCCCGCCCTGTCCGCCCGTGAGCACGAG
ATCCTCGCGCAACTCGCCCGTGGCCTCGGCAACCGGGAGATCGCCCGGGCCCTGTTCATCAGCGAGGCGACGGTCAAGAC
CCATCTGGGGCGGATCTACGGCAAGTTGGGCGTCGAGACCCGGGCCGGCGCGGTGGCCGTGGCCAAGGAACGGCGGCTGC
TGCCGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(153-208)

Response regulator receiver domain (Response_reg)

(13-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B5I5B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.278

97.209

0.372

Multiple sequence alignment