Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RK98_RS10105 Genome accession   NZ_CP026958
Coordinates   1924488..1925204 (-) Length   238 a.a.
NCBI ID   WP_000688493.1    Uniprot ID   G9IE49
Organism   Staphylococcus aureus strain FDAARGOS_40     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1919488..1930204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RK98_RS10085 (RK98_10085) - 1920577..1921527 (+) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -
  RK98_RS10090 (RK98_10090) - 1921676..1923160 (+) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  RK98_RS10095 (RK98_10095) - 1923157..1924116 (+) 960 WP_001253315.1 carbohydrate kinase family protein -
  RK98_RS10100 (RK98_10100) - 1924304..1924413 (-) 110 Protein_1860 hypothetical protein -
  RK98_RS10105 (RK98_10105) agrA 1924488..1925204 (-) 717 WP_000688493.1 quorum-sensing response regulator AgrA Regulator
  RK98_RS10110 (RK98_10110) agrC 1925223..1926506 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  RK98_RS10115 (RK98_10115) agrD 1926536..1926679 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  RK98_RS10120 (RK98_10120) - 1926682..1927245 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  RK98_RS15445 hld 1927535..1927615 (+) 81 WP_000046022.1 delta-hemolysin -
  RK98_RS10130 (RK98_10130) - 1928215..1929000 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  RK98_RS10135 (RK98_10135) - 1929361..1929987 (-) 627 WP_000522381.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27920.92 Da        Isoelectric Point: 6.3009

>NTDB_id=273844 RK98_RS10105 WP_000688493.1 1924488..1925204(-) (agrA) [Staphylococcus aureus strain FDAARGOS_40]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=273844 RK98_RS10105 WP_000688493.1 1924488..1925204(-) (agrA) [Staphylococcus aureus strain FDAARGOS_40]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAAATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-236)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G9IE49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

99.58

0.996

Multiple sequence alignment