Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | RK98_RS06005 | Genome accession | NZ_CP026958 |
| Coordinates | 1138234..1139583 (+) | Length | 449 a.a. |
| NCBI ID | WP_000815646.1 | Uniprot ID | Q9XB96 |
| Organism | Staphylococcus aureus strain FDAARGOS_40 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1102729..1146454 | 1138234..1139583 | within | 0 |
| SCCmec | 1138234..1159599 | 1138234..1139583 | within | 0 |
Gene organization within MGE regions
Location: 1102729..1159599
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RK98_RS05840 (RK98_05840) | - | 1102729..1105881 (-) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
| RK98_RS05845 (RK98_05845) | - | 1106148..1106750 (-) | 603 | WP_000908956.1 | hypothetical protein | - |
| RK98_RS05850 (RK98_05850) | - | 1106958..1107254 (-) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| RK98_RS05855 (RK98_05855) | - | 1107303..1107506 (-) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| RK98_RS05860 (RK98_05860) | - | 1107815..1108801 (+) | 987 | WP_000662022.1 | tRNA dihydrouridine synthase | - |
| RK98_RS15490 | - | 1108987..1109201 (+) | 215 | Protein_1072 | universal stress protein | - |
| RK98_RS05875 (RK98_05875) | sqr | 1109468..1110661 (-) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| RK98_RS05880 (RK98_05880) | cstB | 1110680..1112014 (-) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| RK98_RS05885 (RK98_05885) | cstA | 1112045..1113109 (-) | 1065 | WP_000816124.1 | persulfide response sulfurtransferase CstA | - |
| RK98_RS05890 (RK98_05890) | cstR | 1113246..1113506 (+) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| RK98_RS05895 (RK98_05895) | - | 1113506..1114261 (+) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| RK98_RS05900 (RK98_05900) | - | 1114359..1114447 (+) | 89 | Protein_1078 | hypothetical protein | - |
| RK98_RS05905 (RK98_05905) | - | 1114752..1115107 (+) | 356 | Protein_1079 | tRNA-dihydrouridine synthase | - |
| RK98_RS05910 (RK98_05910) | - | 1115205..1116950 (-) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| RK98_RS05915 (RK98_05915) | - | 1117097..1117189 (-) | 93 | WP_001790000.1 | hypothetical protein | - |
| RK98_RS05920 (RK98_05920) | - | 1117153..1117287 (+) | 135 | WP_001790628.1 | hypothetical protein | - |
| RK98_RS05925 (RK98_05925) | - | 1117537..1119045 (-) | 1509 | WP_001001347.1 | protein kinase domain-containing protein | - |
| RK98_RS05930 (RK98_05930) | - | 1119160..1119786 (+) | 627 | WP_001176969.1 | hypothetical protein | - |
| RK98_RS05940 (RK98_05940) | - | 1120905..1121801 (+) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| RK98_RS05945 (RK98_05945) | - | 1121811..1122680 (+) | 870 | WP_000626133.1 | hypothetical protein | - |
| RK98_RS05950 (RK98_05950) | - | 1123225..1123782 (-) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| RK98_RS05955 (RK98_05955) | - | 1123798..1125819 (-) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| RK98_RS05960 (RK98_05960) | kdpA | 1125838..1127514 (-) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| RK98_RS15495 (RK98_05965) | kdpF | 1127535..1127615 (-) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| RK98_RS05970 (RK98_05970) | - | 1127818..1130451 (+) | 2634 | WP_010922810.1 | sensor histidine kinase | - |
| RK98_RS05975 (RK98_05975) | - | 1130426..1131121 (+) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| RK98_RS05980 (RK98_05980) | - | 1131834..1132769 (+) | 936 | Protein_1093 | YfcC family protein | - |
| RK98_RS15430 | - | 1132976..1133110 (-) | 135 | WP_001792216.1 | hypothetical protein | - |
| RK98_RS05985 (RK98_05985) | - | 1133280..1134421 (+) | 1142 | Protein_1095 | IS3-like element ISSau4 family transposase | - |
| RK98_RS05990 (RK98_05990) | - | 1134672..1135718 (+) | 1047 | WP_001060127.1 | hypothetical protein | - |
| RK98_RS05995 (RK98_05995) | ssb | 1135911..1136207 (+) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| RK98_RS06000 (RK98_06000) | cch1 | 1136207..1138000 (+) | 1794 | WP_000195100.1 | cassette chromosome replicative helicase | - |
| RK98_RS06005 (RK98_06005) | ccrA | 1138234..1139583 (+) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
| RK98_RS06010 (RK98_06010) | ccrB | 1139605..1141233 (+) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| RK98_RS06015 (RK98_06015) | - | 1141751..1142101 (+) | 351 | WP_000859153.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| RK98_RS06020 (RK98_06020) | - | 1142188..1142499 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| RK98_RS06025 (RK98_06025) | - | 1142517..1143023 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| RK98_RS06030 (RK98_06030) | - | 1143044..1143361 (+) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| RK98_RS06035 (RK98_06035) | - | 1143480..1144565 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| RK98_RS06040 (RK98_06040) | - | 1144562..1146454 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| RK98_RS06045 (RK98_06045) | - | 1146461..1146838 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| RK98_RS06050 (RK98_06050) | - | 1146989..1147771 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| RK98_RS06055 (RK98_06055) | erm(A) | 1147897..1148628 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| RK98_RS15525 | - | 1148711..1148770 (-) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| RK98_RS06065 (RK98_06065) | - | 1149162..1149824 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| RK98_RS06075 (RK98_06075) | - | 1150169..1150807 (-) | 639 | Protein_1112 | sulfite exporter TauE/SafE family protein | - |
| RK98_RS06080 (RK98_06080) | cstR | 1150807..1151067 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| RK98_RS06085 (RK98_06085) | - | 1151203..1152267 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| RK98_RS06090 (RK98_06090) | cstB | 1152300..1153634 (+) | 1335 | Protein_1115 | persulfide dioxygenase-sulfurtransferase CstB | - |
| RK98_RS06100 (RK98_06100) | - | 1153748..1154857 (-) | 1110 | WP_025174171.1 | ROK family transcriptional regulator | - |
| RK98_RS06105 (RK98_06105) | psm-mec | 1155212..1155280 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| RK98_RS06110 (RK98_06110) | mecI | 1155365..1155736 (-) | 372 | WP_000369211.1 | mecA-type methicillin resistance repressor MecI | - |
| RK98_RS06115 (RK98_06115) | mecR1 | 1155736..1157493 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| RK98_RS06120 (RK98_06120) | mecA | 1157590..1159599 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52607.20 Da Isoelectric Point: 9.9585
>NTDB_id=273835 RK98_RS06005 WP_000815646.1 1138234..1139583(+) (ccrA) [Staphylococcus aureus strain FDAARGOS_40]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=273835 RK98_RS06005 WP_000815646.1 1138234..1139583(+) (ccrA) [Staphylococcus aureus strain FDAARGOS_40]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
100 |
100 |
1 |
| ccrA | Staphylococcus aureus COL |
74.833 |
100 |
0.748 |