Detailed information NTG0273833

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: D1369_RS17715
• Genome accession: NZ_CP031969
• Coordinates: 3897719..3898843 (+)
• Length: 374 a.a.
• NCBI ID: WP_007383787.1
• Uniprot ID: B5HYI1
• Organism: Streptomyces sp. CC0208
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3892719..3903843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1369_RS17700	-	3893468..3894232 (+)	765	WP_086023215.1	hypothetical protein	-
D1369_RS17705	-	3894321..3895997 (-)	1677	WP_118082522.1	sigma-70 family RNA polymerase sigma factor	-
D1369_RS17710	radA/sms	3896228..3897637 (+)	1410	WP_007383788.1	DNA repair protein RadA	Machinery gene
D1369_RS17715	disA	3897719..3898843 (+)	1125	WP_007383787.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
D1369_RS17720	-	3898959..3899828 (-)	870	WP_082319440.1	hypothetical protein	-
D1369_RS17725	-	3900293..3901255 (+)	963	WP_007383785.1	A/G-specific adenine glycosylase	-
D1369_RS17730	-	3901493..3902035 (+)	543	WP_007383784.1	SigE family RNA polymerase sigma factor	-
D1369_RS17735	-	3902020..3902697 (+)	678	WP_007383783.1	hypothetical protein	-
D1369_RS17740	cseB	3902764..3903468 (+)	705	WP_007383782.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40136.89 Da
• Isoelectric Point: 4.9235

>NTDB_id=273833 D1369_RS17715 WP_007383787.1 3897719..3898843(+) (disA) [Streptomyces sp. CC0208]
MAANDRAAAPGKSGGSAGSDGLMRASLSAVAPGTPLRDGLERVLRGNTGGLIVLGFDKTVETMCTGGFVLDVEFAATRLR
ELCKLDGGIVLSSDLSKILRAGVQFVPDATIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVEEALYELDALTHAELLELPTVARALGYTGSPEAIDSGVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=273833 D1369_RS17715 WP_007383787.1 3897719..3898843(+) (disA) [Streptomyces sp. CC0208]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTTCCGATGGCCTGATGCGCGCCTCCCT
GAGCGCCGTGGCCCCCGGCACCCCCCTGCGCGACGGCCTCGAGCGGGTGCTGCGCGGCAACACCGGCGGACTGATCGTGC
TCGGCTTCGACAAGACCGTGGAGACGATGTGCACGGGCGGTTTCGTCCTGGACGTCGAGTTCGCGGCCACGCGCCTGCGT
GAGCTGTGCAAGCTGGACGGCGGCATCGTGCTCTCGTCCGACCTGTCGAAGATCCTGCGGGCGGGCGTGCAGTTCGTGCC
CGACGCGACGATCCCGACGGAGGAGACGGGCACCCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCGGCTTCCCGG
TCGTCTCGGTCTCCCAGTCGATGCGCCTCATCGCGCTGTACGTCGACGGGCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCGAACCAGGCTCTTGCGACCCTGGAGCGCTACAAGCTGCGCCTGGACGAGGTCGCGGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTCGTGACGGTCCGGGACGTCTCGGCCGTGGCCCAGCGCCTGGAGATGGTCCGCCGTATCG
CGACCGAGATCGCCGAGTACGTGGTCGAGCTCGGCACGGACGGTCGCCTTCTGGCCCTCCAGCTCGACGAGTTGATCGCG
GGCGTGGAGCCGGAACGCGAACTGGTGGTCCGGGACTACGTCCCCGAGCCCACGGCGAAGCGCTCCCGCACGGTCGAGGA
GGCGCTGTACGAACTGGACGCGCTGACCCACGCCGAGCTTCTCGAACTGCCCACCGTGGCCCGCGCCCTGGGCTACACCG
GCTCCCCCGAGGCGATCGACTCGGGTGTCTCTCCGCGGGGCTTCCGCCTCCTGGCCAAGGTCCCCCGTCTGCCCGGCGCG
ATCATCGACCGCCTGGTGGAACACTTCGGCGGTCTCCAGAAGCTGCTGGCAGCCAGCGTCGACGACCTCCAGACGGTGGA
CGGAGTGGGCGAGGCAAGGGCGAGGAGCGTCAGAGAGGGCCTGTCCCGCCTGGCGGAGAGCTCGATCCTGGAACGGTACG
TGTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-296)

3D structure

• AlphaFold DB: B5HYI1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.821	92.513	0.433