Detailed information NTG0273827

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RK98_RS01215
• Genome accession: NZ_CP026958
• Coordinates: 212766..213809 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017146.1
• Uniprot ID: Q7A2Q0
• Organism: Staphylococcus aureus strain FDAARGOS_40
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 207766..218809

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK98_RS01185 (RK98_01185)	-	208187..209443 (-)	1257	WP_001795108.1	aminopeptidase	-
RK98_RS01190 (RK98_01190)	-	209446..209646 (-)	201	WP_000180460.1	DUF1128 family protein	-
RK98_RS01195 (RK98_01195)	-	209793..210257 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RK98_RS01200 (RK98_01200)	-	210264..210539 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RK98_RS01205 (RK98_01205)	-	210817..212034 (+)	1218	WP_000037068.1	YihY/virulence factor BrkB family protein	-
RK98_RS01210 (RK98_01210)	vraR	212147..212776 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RK98_RS01215 (RK98_01215)	vraS	212766..213809 (-)	1044	WP_001017146.1	sensor histidine kinase	Regulator
RK98_RS01220 (RK98_01220)	liaF	213806..214507 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RK98_RS01225 (RK98_01225)	-	214522..214908 (-)	387	WP_001110179.1	hypothetical protein	-
RK98_RS01230 (RK98_01230)	map	215125..215883 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RK98_RS01240 (RK98_01240)	-	216414..217400 (+)	987	WP_000999717.1	FUSC family protein	-
RK98_RS01250 (RK98_01250)	-	217831..218244 (-)	414	WP_001557448.1	hypothetical protein	-
RK98_RS01255 (RK98_01255)	-	218273..218383 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40045.46 Da
• Isoelectric Point: 6.0577

>NTDB_id=273827 RK98_RS01215 WP_001017146.1 212766..213809(-) (vraS) [Staphylococcus aureus strain FDAARGOS_40]
MNHYNRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=273827 RK98_RS01215 WP_001017146.1 212766..213809(-) (vraS) [Staphylococcus aureus strain FDAARGOS_40]
ATGAACCACTACAATAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• PDB: 4GT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997