Detailed information NTG0273819

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RL01_RS11515
• Genome accession: NZ_CP026957
• Coordinates: 2238945..2239832 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain FDAARGOS_43
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2233945..2244832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RL01_RS11485 (RL01_11485)	-	2234677..2235438 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
RL01_RS11490 (RL01_11490)	-	2235683..2236138 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RL01_RS14845 (RL01_11495)	-	2236260..2236361 (+)	102	WP_000731972.1	SE2200 family small protein	-
RL01_RS11500 (RL01_11500)	-	2236421..2237845 (-)	1425	WP_000953748.1	alkaline phosphatase	-
RL01_RS11505 (RL01_11505)	-	2238043..2238243 (+)	201	WP_000604727.1	hypothetical protein	-
RL01_RS11510 (RL01_11510)	braR	2238269..2238934 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RL01_RS11515 (RL01_11515)	braS	2238945..2239832 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RL01_RS11520 (RL01_11520)	-	2239940..2240695 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RL01_RS11525 (RL01_11525)	-	2240692..2242692 (+)	2001	WP_000776740.1	ABC transporter permease	-
RL01_RS11530 (RL01_11530)	-	2243351..2243464 (+)	114	Protein_2143	hypothetical protein	-
RL01_RS11540 (RL01_11540)	-	2243846..2244106 (+)	261	WP_001791974.1	hypothetical protein	-
RL01_RS11545 (RL01_11545)	-	2244116..2244613 (+)	498	WP_001065268.1	glutathione peroxidase	-
RL01_RS11550 (RL01_11550)	-	2244721..2244813 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=273819 RL01_RS11515 WP_000143417.1 2238945..2239832(+) (braS) [Staphylococcus aureus strain FDAARGOS_43]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=273819 RL01_RS11515 WP_000143417.1 2238945..2239832(+) (braS) [Staphylococcus aureus strain FDAARGOS_43]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99