Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   RL01_RS10840 Genome accession   NZ_CP026957
Coordinates   2085137..2086486 (+) Length   449 a.a.
NCBI ID   WP_000815641.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FDAARGOS_43     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2079530..2094901 2085137..2086486 within 0


Gene organization within MGE regions


Location: 2079530..2094901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL01_RS10820 (RL01_10820) - 2079530..2081020 (-) 1491 WP_000554504.1 RNA-binding domain-containing protein -
  RL01_RS10825 (RL01_10825) - 2081638..2082687 (-) 1050 WP_000613248.1 hypothetical protein -
  RL01_RS10830 (RL01_10830) ssb 2082826..2083116 (+) 291 WP_001036438.1 cassette chromosome ssDNA-binding protein -
  RL01_RS10835 (RL01_10835) cch1 2083116..2084903 (+) 1788 WP_000122620.1 cassette chromosome replicative helicase -
  RL01_RS10840 (RL01_10840) ccrA 2085137..2086486 (+) 1350 WP_000815641.1 cassette chromosome recombinase CcrA Machinery gene
  RL01_RS10845 (RL01_10845) ccrB 2086508..2088136 (+) 1629 WP_001186600.1 cassette chromosome recombinase CcrB Machinery gene
  RL01_RS10850 (RL01_10850) - 2088658..2089008 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  RL01_RS10860 (RL01_10860) - 2089095..2089406 (+) 312 WP_000700851.1 DUF960 family protein -
  RL01_RS10865 (RL01_10865) - 2089421..2089927 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  RL01_RS10870 (RL01_10870) - 2089976..2091586 (+) 1611 Protein_2018 IS1182 family transposase -
  RL01_RS10875 (RL01_10875) - 2091577..2091819 (-) 243 Protein_2019 type I restriction enzyme endonuclease domain-containing protein -
  RL01_RS10880 (RL01_10880) - 2091809..2092795 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  RL01_RS10885 (RL01_10885) mecA 2092892..2094901 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52582.27 Da        Isoelectric Point: 10.0414

>NTDB_id=273814 RL01_RS10840 WP_000815641.1 2085137..2086486(+) (ccrA) [Staphylococcus aureus strain FDAARGOS_43]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQKQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQNTIQ
NIIQKRFTLNMLYPYIDEILITKSKTLMGIYFKNEPLNIVNQTTQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=273814 RL01_RS10840 WP_000815641.1 2085137..2086486(+) (ccrA) [Staphylococcus aureus strain FDAARGOS_43]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATTAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAAAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAAAACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATGCTGTATCCCTACATTGATGAAATTCTTATCACAAAAAGTAAAACACT
AATGGGTATCTATTTCAAAAATGAACCCTTAAACATCGTCAATCAAACAACGCAATCGTCAATTGCATAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(169-248)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

95.546

100

0.955
  ccrA Staphylococcus aureus COL

76.169

100

0.762

Multiple sequence alignment