Detailed information NTG0273781

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RL01_RS00890
• Genome accession: NZ_CP026957
• Coordinates: 145358..146401 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_43
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 140358..151401

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RL01_RS00850 (RL01_00850)	-	140724..140835 (+)	112	Protein_161	hypothetical protein	-
RL01_RS00855 (RL01_00855)	-	140864..141277 (+)	414	WP_001837236.1	hypothetical protein	-
RL01_RS00865 (RL01_00865)	-	141767..142753 (-)	987	WP_000999713.1	FUSC family protein	-
RL01_RS00875 (RL01_00875)	map	143284..144042 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RL01_RS00880 (RL01_00880)	-	144259..144645 (+)	387	WP_001110179.1	hypothetical protein	-
RL01_RS00885 (RL01_00885)	liaF	144660..145361 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RL01_RS00890 (RL01_00890)	vraS	145358..146401 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RL01_RS00895 (RL01_00895)	vraR	146391..147020 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RL01_RS00900 (RL01_00900)	-	147132..148343 (-)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
RL01_RS00905 (RL01_00905)	-	148621..148896 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
RL01_RS00910 (RL01_00910)	-	148903..149367 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RL01_RS00915 (RL01_00915)	-	149514..149714 (+)	201	WP_000180460.1	DUF1128 family protein	-
RL01_RS00920 (RL01_00920)	-	149717..150973 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=273781 RL01_RS00890 WP_001017131.1 145358..146401(+) (vraS) [Staphylococcus aureus strain FDAARGOS_43]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=273781 RL01_RS00890 WP_001017131.1 145358..146401(+) (vraS) [Staphylococcus aureus strain FDAARGOS_43]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1