Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   RL06_RS07155 Genome accession   NZ_CP026953
Coordinates   1324540..1325901 (-) Length   453 a.a.
NCBI ID   WP_016170667.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FDAARGOS_48     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 1316170..1325901 1324540..1325901 within 0


Gene organization within MGE regions


Location: 1316170..1325901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL06_RS07110 (RL06_07110) mecA 1316170..1318179 (-) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  RL06_RS07115 (RL06_07115) - 1318276..1319262 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  RL06_RS07120 (RL06_07120) - 1319252..1319494 (+) 243 Protein_1315 type I restriction enzyme endonuclease domain-containing protein -
  RL06_RS07125 (RL06_07125) - 1319485..1321095 (-) 1611 Protein_1316 IS1182 family transposase -
  RL06_RS07130 (RL06_07130) - 1321144..1321650 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  RL06_RS07135 (RL06_07135) - 1321666..1321977 (-) 312 WP_016170671.1 DUF960 family protein -
  RL06_RS07145 (RL06_07145) - 1322064..1322414 (-) 351 WP_016170669.1 SAUGI family uracil-DNA glycosylase inhibitor -
  RL06_RS07150 (RL06_07150) ccrB 1322915..1324543 (-) 1629 WP_016170668.1 cassette chromosome recombinase CcrB Machinery gene
  RL06_RS07155 (RL06_07155) ccrA 1324540..1325901 (-) 1362 WP_016170667.1 cassette chromosome recombinase CcrA Machinery gene

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 53527.41 Da        Isoelectric Point: 10.0266

>NTDB_id=273761 RL06_RS07155 WP_016170667.1 1324540..1325901(-) (ccrA) [Staphylococcus aureus strain FDAARGOS_48]
MEEVIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVTFYDDKRSGRNTKRSGYKKIVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDRFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYRYR
QGHFVVYEEEVHTVKAVYRLYLQGLGYKKISQHLDNNSKLIPRKPYQVRNILLNPNYCGRVINKYGTFNNIVPPIIDVDT
FEEAQERRIHKQHNRSNSRNKLKRRIKCPYCQSTLTNLTIKKEHHSLRYYVCPKNMNDAYRTCPFKGINAPELESKVLDT
CKKYFEEQSFHNRLNDTILKVLKQQQMKHRQSHLTQEQLIEKLAQNQIDIETFKRLSTSYESEERYSNYSHKQMAEAVRH
VIKDKLTLETIAPLIDDITITQTKQLQRIYFKNSPFNIVEQSHLITPERNEVI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=273761 RL06_RS07155 WP_016170667.1 1324540..1325901(-) (ccrA) [Staphylococcus aureus strain FDAARGOS_48]
ATGGAAGAAGTTATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACTGCTAAGCAATATGGATGGTCTAATGTGACATTTTATGATGATAAGAGAAGCGGTCGAAATACAAAACGTTCAGGCT
ATAAAAAAATAGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGTCTGAATCGACTCCATCGTAAT
TTGAAAAATGCTATACAATTCTTTGAAATTTGCAAAAAGCATCACGTCACAATCATCAGCGTGAATGATGGTTATTTTGA
CTTATCTAAAGAATTTGATCGCTTTCGCCTAAACATACTTATGAGTCTAGCTGAAATGGAGTCTAATAATATCAGTGAAC
AGACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCACCTTTTGGCTATCGTTATAGA
CAAGGTCATTTTGTTGTATATGAAGAAGAAGTCCATACAGTCAAAGCAGTTTATCGCTTGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTAGATAATAATTCTAAGCTTATTCCACGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGTGGTCGTGTCATCAATAAGTATGGAACGTTTAATAATATCGTTCCGCCTATTATTGATGTTGATACG
TTTGAAGAAGCACAAGAGCGGCGTATTCATAAACAACACAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACAATAAAAAAAGAACATCATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAGGTATCAATGCACCAGAACTTGAAAGTAAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAATCGATTGAATGACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCACAGACAATCACATCTAACACAAGAACAACTCATCGAAAAATTAGCACAAAATCAAATTGACATAGAAACATTTA
AACGGTTATCTACTAGCTATGAAAGTGAAGAACGTTACTCTAATTATTCACATAAACAAATGGCCGAAGCAGTCCGTCAT
GTTATCAAAGATAAATTGACATTAGAAACCATAGCACCTTTGATTGATGACATTACAATAACTCAAACTAAACAGTTACA
AAGAATCTACTTTAAAAATAGTCCATTCAATATCGTTGAACAATCGCATTTAATAACTCCTGAAAGGAATGAAGTCATAT
GA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(168-248)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

55.305

97.792

0.541
  ccrA Staphylococcus aureus N315

51.693

97.792

0.506

Multiple sequence alignment