Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RL06_RS03180 Genome accession   NZ_CP026953
Coordinates   557219..557935 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain FDAARGOS_48     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 552219..562935
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL06_RS03150 (RL06_03150) - 552436..553062 (+) 627 WP_000522384.1 nitroreductase family protein -
  RL06_RS03155 (RL06_03155) - 553423..554208 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  RL06_RS15175 hld 554808..554888 (-) 81 WP_000046022.1 delta-hemolysin -
  RL06_RS03165 (RL06_03165) - 555178..555741 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  RL06_RS03170 (RL06_03170) agrD 555744..555887 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  RL06_RS03175 (RL06_03175) agrC 555917..557200 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  RL06_RS03180 (RL06_03180) agrA 557219..557935 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  RL06_RS03185 (RL06_03185) - 558007..558116 (+) 110 Protein_582 hypothetical protein -
  RL06_RS03190 (RL06_03190) - 558304..559263 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  RL06_RS03195 (RL06_03195) - 559260..560744 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  RL06_RS03200 (RL06_03200) - 560893..561843 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=273752 RL06_RS03180 WP_000688492.1 557219..557935(+) (agrA) [Staphylococcus aureus strain FDAARGOS_48]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=273752 RL06_RS03180 WP_000688492.1 557219..557935(+) (agrA) [Staphylococcus aureus strain FDAARGOS_48]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment