Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   D1O36_RS07915 Genome accession   NZ_CP031881
Coordinates   1467351..1469456 (-) Length   701 a.a.
NCBI ID   WP_134973439.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST106     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1462351..1474456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1O36_RS07885 (D1O36_07915) pptB 1462823..1463860 (-) 1038 WP_023909891.1 ABC transporter permease Regulator
  D1O36_RS07890 (D1O36_07920) pptA 1463857..1464588 (-) 732 WP_084829044.1 ABC transporter ATP-binding protein Regulator
  D1O36_RS07895 (D1O36_07925) - 1464653..1465072 (+) 420 WP_084829045.1 HIT family protein -
  D1O36_RS07900 (D1O36_07930) - 1465069..1465368 (+) 300 WP_084829809.1 hypothetical protein -
  D1O36_RS07905 (D1O36_07935) - 1465419..1466147 (-) 729 WP_134973435.1 hypothetical protein -
  D1O36_RS07910 (D1O36_07940) - 1466163..1466756 (-) 594 WP_134973437.1 DUF4230 domain-containing protein -
  D1O36_RS11100 - 1466815..1466940 (-) 126 WP_011681534.1 hypothetical protein -
  D1O36_RS07915 (D1O36_07945) clpE 1467351..1469456 (-) 2106 WP_134973439.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  D1O36_RS07920 (D1O36_07950) - 1470172..1471263 (-) 1092 WP_134973441.1 nucleotidyltransferase -
  D1O36_RS07925 (D1O36_07955) - 1471270..1472010 (-) 741 WP_280632115.1 class I SAM-dependent methyltransferase -
  D1O36_RS07935 (D1O36_07965) rsfS 1472335..1472688 (-) 354 WP_011227491.1 ribosome silencing factor -
  D1O36_RS07940 (D1O36_07970) yqeK 1472712..1473302 (-) 591 WP_002951696.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  D1O36_RS07945 (D1O36_07975) - 1473299..1473931 (-) 633 WP_002951698.1 nicotinate-nucleotide adenylyltransferase -
  D1O36_RS07950 (D1O36_07980) yhbY 1474035..1474352 (-) 318 WP_002951701.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77493.41 Da        Isoelectric Point: 4.7980

>NTDB_id=272605 D1O36_RS07915 WP_134973439.1 1467351..1469456(-) (clpE) [Streptococcus thermophilus strain ST106]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQQGNGPKQDGILAKIGRN
LTQEAREGKLDPVIRRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVSGDVPAAIKDKEIISIDISALEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILK
NPALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQH
PVTDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMDNHLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYESNLTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEA
AKAYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=272605 D1O36_RS07915 WP_134973439.1 1467351..1469456(-) (clpE) [Streptococcus thermophilus strain ST106]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACAGGGTAACGGACCTAAACAAGATGGTATTCTTGCTAAAATTGGTCGTAAC
TTGACTCAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCAGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCAC
AAGCCATCGTTAGTGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AATCCTGCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACAT
CCAGTAACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGA
TTACGAAGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGG
TGACTGCGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGAT
ATCGAACGTTTGAAAGATATGGATAACCATTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACG
TTCCATCCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATAC
CTTGACAGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCA
CCCTTCTCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATT
ATCGCAACTTCAAACGCTGGCTTTGGTTACGAATCTAACTTGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTT
GAAACCTTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTT
CTAAGATTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(257-351)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-235)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.505

100

0.465
  clpC Lactococcus lactis subsp. cremoris KW2

48.694

92.867

0.452
  clpE Streptococcus pneumoniae R6

47.975

91.583

0.439
  clpE Streptococcus pneumoniae Rx1

47.975

91.583

0.439
  clpE Streptococcus pneumoniae D39

47.975

91.583

0.439
  clpE Streptococcus pneumoniae TIGR4

47.894

91.441

0.438
  clpC Bacillus subtilis subsp. subtilis str. 168

44.812

94.864

0.425
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.871

93.01

0.389
  clpC Streptococcus thermophilus LMD-9

43.76

88.017

0.385
  clpC Streptococcus thermophilus LMG 18311

43.598

88.017

0.384
  clpC Streptococcus pneumoniae TIGR4

42.926

88.73

0.381
  clpC Streptococcus pneumoniae Rx1

42.926

88.73

0.381
  clpC Streptococcus pneumoniae D39

42.926

88.73

0.381
  clpC Streptococcus mutans UA159

42.605

88.73

0.378