Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NMC_RS02010 Genome accession   NC_008767
Coordinates   376847..379963 (-) Length   1038 a.a.
NCBI ID   WP_011798779.1    Uniprot ID   A1KS50
Organism   Neisseria meningitidis FAM18     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 371847..384963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMC_RS13525 - 372410..372577 (-) 168 WP_153312129.1 hypothetical protein -
  NMC_RS01980 (NMC0366) - 372581..372970 (-) 390 WP_002221514.1 endonuclease domain-containing protein -
  NMC_RS02000 (NMC0369) - 373550..373687 (-) 138 WP_002214606.1 VOC family protein -
  NMC_RS02005 (NMC0370) carA 373733..374866 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  NMC_RS02010 (NMC0371) pilC 376847..379963 (-) 3117 WP_011798779.1 PilC family type IV pilus tip adhesin Machinery gene
  NMC_RS02015 (NMC0372) apbC 380917..381996 (-) 1080 WP_002248129.1 iron-sulfur cluster carrier protein ApbC -
  NMC_RS02025 (NMC0373) - 382366..382875 (+) 510 WP_002221509.1 protein disulfide oxidoreductase -
  NMC_RS02035 (NMC0374) nadR 383218..383658 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  NMC_RS02040 (NMC0375) hpaC 383773..384273 (+) 501 WP_002221506.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1038 a.a.        Molecular weight: 113918.75 Da        Isoelectric Point: 9.7094

>NTDB_id=27222 NMC_RS02010 WP_011798779.1 376847..379963(-) (pilC) [Neisseria meningitidis FAM18]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTYKYAIIMNEQNQPKVKQEGSYSTLREKDRERKFIYNKGGSGGGSVS
FNNSDELVSQQSGTAVFGTATYLPPYGKVSGFDADALKERNNALNWINTTRPGLAGYSYANVICRDTRQCPQLFYETKFA
FSNKDLVNNAGRLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSEGTAKDGKVSNKLISSFSEDNNNQTIVSTTRDHPISL
GDQQREHTAMAYYLNAKLHLLDKKGIKDIAQGKTVDLGTLRPRVETKTNNWGNLLNFWVTWKIEDNGQIPVKLGLPEVKA
GRCTNAAHPNSKAKPPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPGRPGRYSLAALDAQNI
KSHEPRFNGRQTVIRLPGGVYKISLGRNGGRVAGINGNDGKNDTFGIFKDRYVTPEADEWSEMLLPWTVRAFNDDGRFNT
VNKEENNGKPKYSQRYRIRENGNNGKRDLGDIVNSPIVAVGGYLATSANDGMVHIFKQSGGDKRGYNLKLSYIPGTMPRK
NIENNDSTLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGFGGRGAYALDLTKADDNDPTKASLFD
VKDNGNNGNNGNNRVELGYTVGTPQIGKTHNGKYAAFLASGYATKKIDDPTNKTALYVYDLENNNGTPIAKIEVPNGKGG
LSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSNNDPTKWSVRTIFKGTPDKPITSAPAVSKLKDKRVVIFGTGSDLSED
DVDKKDIQSIYGIFDNDTGTDVAEEGQGKGLLEQHLTQEDKTLFLTDYKRSDGSGDKGWVVKLEAGQRVTVKPTVVLRTA
FVTIRKYNDGGCGAETAILGINTADGGKLTKKSARPIVPEANTAVAQYSGHKQTAKGKSIPIGCMWKNNETVCPNGYVYD
KPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREIFY

Nucleotide


Download         Length: 3117 bp        

>NTDB_id=27222 NMC_RS02010 WP_011798779.1 376847..379963(-) (pilC) [Neisseria meningitidis FAM18]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCTATAAATACGCTATTATCATGAACGAACAAAATCAGCCGAAGGTAAAGCAGGAGGGTT
CATATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAGGCGGATCGGGTGGAGGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCAACAATGCCCTTAATTGGATTAATACGACCCGCCCGGGGT
TGGCAGGCTACTCCTACGCCAACGTCATATGCAGAGACACAAGGCAATGCCCCCAACTTTTCTATGAGACCAAATTTGCC
TTCAGCAACAAAGATTTGGTAAACAATGCGGGCAGGCTGGATAGGCACCCGGACCCAAGCCGCGAAAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGGGTACCGCCAAAGATGGCAAGGTATCCA
ACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACACGAGACCACCCTATTTCCCTT
GGCGACCAGCAGCGCGAACATACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGATTAA
AGATATCGCCCAAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGACGAAGACAAATAATTGGGGGAATC
TGCTAAATTTTTGGGTTACGTGGAAGATTGAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAAGTCAAAGCC
GGGCGCTGCACCAACGCCGCCCACCCCAATTCCAAAGCCAAACCCCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTT
CGGCCCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGGCAGTTCGAGCAGCCGCATCT
TCCTCCAAGAGCTGAAAACTCAAACCGACCCCGGCAGGCCCGGCCGGTATTCCCTCGCCGCTTTGGATGCGCAGAACATC
AAAAGCCACGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGCCGGGCGGCGTGTACAAGATCAGCCTGGGCAG
GAACGGCGGCCGGGTCGCGGGTATTAATGGCAATGACGGCAAAAACGACACTTTCGGCATCTTCAAGGACAGGTATGTCA
CACCTGAGGCCGACGAGTGGAGCGAAATGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACA
GTCAACAAAGAAGAAAACAACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAAGCG
TGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGGCAACTTCTGCCAACGACGGGATGGTGC
ATATCTTCAAACAAAGCGGCGGGGACAAGCGCGGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAG
AATATTGAAAACAACGACTCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGG
CGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACACTTCTTTATGTTCGGCGCAATGG
GCTTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGACGACAATGACCCGACAAAAGCCTCTTTGTTTGAT
GTAAAAGATAACGGCAATAATGGCAATAACGGCAATAATCGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGG
CAAAACCCACAACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATGCGACTAAAAAAATTGACGACCCAACAAATAAAA
CCGCGCTGTATGTGTATGATTTGGAAAACAACAACGGTACGCCGATTGCAAAAATCGAAGTACCCAACGGCAAGGGCGGG
CTTTCGTCCCCCACGTTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGACCGCGGCGGGAATAT
GTACCGCTTTGATTTGAGCAACAACGATCCGACCAAATGGTCTGTACGTACTATTTTTAAAGGCACGCCGGATAAGCCGA
TTACCTCCGCGCCCGCCGTTTCCAAACTGAAAGACAAACGCGTGGTTATCTTCGGTACGGGCAGTGATTTGAGTGAGGAT
GATGTTGATAAAAAGGATATACAATCTATTTACGGTATTTTTGACAATGACACAGGCACGGATGTGGCAGAAGAAGGACA
GGGCAAAGGGTTGCTCGAGCAACACCTTACTCAGGAAGATAAAACCTTATTCCTGACCGATTACAAGCGATCCGACGGCT
CGGGCGACAAGGGCTGGGTAGTGAAATTGGAAGCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCC
TTTGTAACCATCCGCAAATATAACGACGGCGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACTGCCGACGGCGG
CAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGAAGCCAATACGGCTGTCGCGCAATATTCCGGTCATAAGCAAA
CCGCCAAAGGCAAATCCATCCCTATAGGTTGTATGTGGAAAAACAATGAAACCGTCTGCCCGAACGGATATGTTTACGAC
AAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAG
CGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGA
ACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAATCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(509-846)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KS50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

77.82

100

0.784

Multiple sequence alignment