Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NMC_RS00175 Genome accession   NC_008767
Coordinates   34401..37547 (+) Length   1048 a.a.
NCBI ID   WP_011798740.1    Uniprot ID   A1KR81
Organism   Neisseria meningitidis FAM18     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 29401..42547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMC_RS11505 - 30156..30437 (-) 282 WP_011798768.1 hypothetical protein -
  NMC_RS00145 (NMC0027) - 30552..30854 (-) 303 WP_002219942.1 hypothetical protein -
  NMC_RS00150 (NMC0028) - 30882..31112 (-) 231 WP_002216898.1 hypothetical protein -
  NMC_RS00155 (NMC0029) - 31339..31539 (-) 201 WP_002212530.1 hypothetical protein -
  NMC_RS00160 (NMC0030) - 31543..31854 (-) 312 WP_002212531.1 hypothetical protein -
  NMC_RS00165 (NMC0031) - 31875..33083 (-) 1209 WP_002212532.1 replication initiation factor domain-containing protein -
  NMC_RS00175 (NMC0033) pilC 34401..37547 (+) 3147 WP_011798740.1 PilC family type IV pilus tip adhesin Machinery gene
  NMC_RS00180 (NMC0034) yccS 38697..40847 (-) 2151 WP_002220096.1 YccS family putative transporter -
  NMC_RS00185 (NMC0035) - 41133..42359 (-) 1227 WP_002218483.1 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 1048 a.a.        Molecular weight: 115380.32 Da        Isoelectric Point: 9.7417

>NTDB_id=27216 NMC_RS00175 WP_011798740.1 34401..37547(+) (pilC) [Neisseria meningitidis FAM18]
MNKTWKRQVFRHTALYTAILMFSHTGGGGGAQAQENPYAIVMNSQKLPEVKWGNSYKKGELRPEDRDRKFTFTSTYGIKR
NTNITFNNTDYLVSEKNGTAVFGAATYLPPYGKVSGFDTDRLTKRGNAVDWINTTHPGLIGYSYQGITCSSSSSCPEFGY
KTQFTFGNSGLAKKTNSSKLDIYEDKSRDNSPIYKLQDYPWLGVSFNLSSDSYVKQKRHNSLVSSFSEDVTQSNGTQSPY
KDRNLVYRTDDYHNKGNYSHQDAHHAIAFYLNAKLHLLDKKQIKNIAQGSELNLGMLKTHIELPKNFNQRSLVGSVVSWT
VKDEGKVSVKLKLPEVKAGRCINKDNPNPKSKAPSPALTAPALWFGPVQNGKAQMYSASVSTYPDSSSSRIFLQNLKRKD
DPNKPGRHSLATLTENDIKNREPTFNQRQTIIRLDGGVQQIKLDKSNEATGLNGNTNNNTFGIVKDLGVDPDANEWKKVL
LPWTVRAFNDDGRFNTVNKEENNGKPKYSQKYRSRDNGKHERNLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRS
YNLKLSYIPGTMPRKDIQNTESTLAKELRAFAEKSYVGDRYGVDGGFVLRKVERNGKDHVFMFGAMGFGGRGAYALDLSK
IDSGNGNLADVSLFDVKHDKNGNNGVKLGYTVGTPQIGKTHDGKYAAFLASGYATKDITSGDNKTALYVYDLESSGTLIK
KIEVPNGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSNNDPTKWSVRTIFKGTPDKPITSAPAVSKLKDKRVVI
FGTGSDLSEDDVDKKDIQSIYGIFDNDTGTDVAEEGQGKGLLEQHLTQEDKTLFLTDYKRSDGSGDKGWVVKLEAGQRVT
VKPTVVLRTAFVTIRKYNDGGCGAETAILGINTADGGKLTKKSARPIVPEANTAVAQYSGHKQTAKGKSIPIGCMWKNNE
TVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKR
ISWREVFY

Nucleotide


Download         Length: 3147 bp        

>NTDB_id=27216 NMC_RS00175 WP_011798740.1 34401..37547(+) (pilC) [Neisseria meningitidis FAM18]
ATGAATAAAACTTGGAAACGGCAGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGCAGGCGCAGGAGAATCCATACGCTATTGTAATGAACAGTCAAAAGCTGCCCGAGGTAAAGTGGGGGA
ATTCATATAAAAAAGGGGAGTTGAGGCCCGAAGACAGGGATCGTAAATTTACCTTTACGAGTACTTATGGAATCAAACGC
AACACTAATATCACATTCAATAATACCGATTATCTTGTTTCTGAAAAAAACGGTACTGCCGTTTTCGGCGCGGCGACCTA
CCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGACCAAGCGCGGCAATGCCGTTGATTGGATTAATA
CGACCCACCCGGGGTTGATAGGCTACAGCTACCAAGGTATCACATGCAGCAGCAGCAGCAGCTGTCCTGAATTTGGCTAT
AAAACCCAATTTACCTTCGGTAATTCCGGTTTGGCAAAAAAGACAAACAGCAGCAAGCTGGATATATACGAAGACAAAAG
CCGCGACAATTCGCCCATTTACAAATTGCAGGATTATCCTTGGTTGGGCGTGTCTTTCAATTTGAGCAGCGATAGCTACG
TCAAACAAAAGAGACACAATAGTTTGGTATCTTCTTTTAGCGAGGATGTGACGCAGAGCAATGGTACGCAAAGCCCATAC
AAAGACAGAAACCTCGTTTATCGTACAGACGATTACCATAATAAGGGTAATTATAGCCATCAGGACGCACACCACGCCAT
CGCCTTTTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACAAATCAAAAATATCGCGCAAGGCAGTGAACTTAATT
TGGGTATGTTGAAAACGCACATCGAGCTGCCGAAAAATTTTAATCAAAGGAGCTTGGTAGGTTCGGTGGTTAGTTGGACG
GTTAAAGATGAGGGAAAAGTCAGCGTCAAACTCAAATTGCCGGAAGTCAAAGCAGGCCGCTGCATCAACAAAGATAACCC
CAATCCCAAATCCAAAGCCCCTTCCCCCGCCCTGACCGCCCCCGCGCTGTGGTTCGGACCTGTGCAAAATGGTAAGGCGC
AGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCCGCATTTTCCTTCAAAATCTGAAAAGAAAAGAC
GACCCCAACAAACCCGGCCGCCATTCCCTCGCAACCTTGACTGAGAATGATATTAAAAATCGAGAGCCGACTTTCAACCA
GCGGCAAACAATCATCCGATTGGATGGCGGCGTACAGCAGATCAAACTGGATAAAAGCAATGAGGCCACCGGTTTAAATG
GAAATACCAACAACAACACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTGATGCCAATGAGTGGAAAAAAGTATTG
CTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACAGTCAACAAAGAAGAAAACAACGGCAAGCCAAA
ATACAGTCAAAAATACCGCAGCCGCGACAACGGCAAGCACGAGCGCAATTTGGGCGACATCGTCAACAGCCCCATCGTGG
CGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCGGCGGGGACAAGCGCAGC
TACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAGGATATTCAAAACACCGAATCCACCCTTGCCAAAGA
GCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCAAAGTCGAAC
GGAACGGGAAAGACCATGTGTTTATGTTCGGCGCGATGGGCTTTGGCGGCAGAGGCGCGTATGCCTTGGATTTAAGCAAA
ATCGACAGCGGCAACGGCAACCTGGCAGACGTTTCCCTGTTTGATGTCAAACATGACAAGAATGGCAATAACGGCGTGAA
ATTAGGCTACACCGTCGGCACACCGCAAATCGGCAAAACCCACGACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATG
CGACTAAAGACATTACCAGCGGCGACAATAAAACCGCGCTGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAA
AAAATCGAAGTACCCAACGGCAAGGGCGGGCTTTCGTCCCCCACGTTGGTGGATAAAGATTTGGACGGCACGGTCGATAT
CGCCTATGCCGGCGACCGCGGCGGGAATATGTACCGCTTTGATTTGAGCAACAACGATCCGACCAAATGGTCTGTACGTA
CTATTTTTAAAGGCACGCCGGATAAGCCGATTACCTCCGCGCCCGCCGTTTCCAAACTGAAAGACAAACGCGTGGTTATC
TTCGGTACGGGCAGTGATTTGAGTGAGGATGATGTTGATAAAAAGGATATACAATCTATTTACGGTATTTTTGACAATGA
CACAGGCACGGATGTGGCAGAAGAAGGACAGGGCAAAGGGTTGCTCGAGCAACACCTTACTCAGGAAGATAAAACCTTAT
TCCTGACCGATTACAAGCGATCCGACGGCTCGGGCGACAAGGGCTGGGTAGTGAAATTGGAAGCCGGACAGCGCGTTACC
GTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATAACGACGGCGGCTGCGGCGCGGAAACCGC
CATTTTGGGCATCAATACTGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGAAGCCAATACGG
CTGTCGCGCAATATTCCGGTCATAAGCAAACCGCCAAAGGCAAATCCATCCCTATAGGTTGTATGTGGAAAAACAATGAA
ACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTC
AACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCT
CCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGA
ATCAGCTGGCGCGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(524-856)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KR81

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.505

100

0.735

Multiple sequence alignment