Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   D1112_RS03255 Genome accession   NZ_CP031854
Coordinates   727210..729231 (-) Length   673 a.a.
NCBI ID   WP_012262909.1    Uniprot ID   -
Organism   Actinobacillus pleuropneumoniae strain ORG1224     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 722210..734231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1112_RS03235 (D1112_03245) - 723987..725210 (-) 1224 WP_012262907.1 ATP-binding protein -
  D1112_RS03240 (D1112_03250) - 725346..725735 (-) 390 WP_005614926.1 type II toxin-antitoxin system VapC family toxin -
  D1112_RS03245 (D1112_03255) - 725736..725996 (-) 261 WP_005604117.1 antitoxin -
  D1112_RS03250 (D1112_03260) - 726342..727178 (+) 837 WP_012262908.1 DUF6216 family protein -
  D1112_RS03255 (D1112_03265) uvrB 727210..729231 (-) 2022 WP_012262909.1 excinuclease ABC subunit UvrB Machinery gene
  D1112_RS03260 (D1112_03275) efeO 729408..730220 (+) 813 WP_005607533.1 iron uptake system protein EfeO -
  D1112_RS03265 (D1112_03280) efeB 730232..731425 (+) 1194 WP_005614931.1 iron uptake transporter deferrochelatase/peroxidase subunit -
  D1112_RS03270 (D1112_03285) - 731436..732056 (+) 621 WP_012262911.1 hypothetical protein -
  D1112_RS03275 (D1112_03290) - 732096..732914 (-) 819 WP_012262912.1 PHP domain-containing protein -
  D1112_RS03280 (D1112_03295) - 732918..733508 (-) 591 WP_237601078.1 DNA glycosylase -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76692.49 Da        Isoelectric Point: 5.1545

>NTDB_id=271677 D1112_RS03255 WP_012262909.1 727210..729231(-) (uvrB) [Actinobacillus pleuropneumoniae strain ORG1224]
MSKQGKPFILHSPFKPSGDQPSAIAKLTEGLNDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYAEM
KAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINEQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDVDAYMQM
MLHLQVGAIIDQREILARLAELQYTRNDQAFQRSTFRVRGEVIDIFPAESDEIALRVELFDDEIESLSLFDPLTGHSLGK
VPRYTIYPKTHYVTPRERILNAIEEIKQELVERREYFIKENKLLEEQRITQRTQFDIEMMNELGYCSGIENYSRYLSGRK
EGEPPPTLFDYMPADGLLIIDESHVTVPQIGGMYRGDRARKETLVQYGFRLPSALDNRPLRFEEFERLAPQTIYVSATPG
NYELEKSNGDVVDQVVRPTGLLDPIIEVRPVATQVDDVLSEIHKRVAVDERVLITTLTKKMAEDLTDYLDEHGVRVRYLH
SDIDTVERVEIIHDLRMGMFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYGDRI
TNSMQKAITETERRREKQQKYNEEHGITPQALNKKVGELLDIGQTDKPKRGKQAVKIEEKSANTYKPKSRKELEKELKQL
EQQMRDFAKDLEFEKAAAVRDKIGQLKAVLLEI

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=271677 D1112_RS03255 WP_012262909.1 727210..729231(-) (uvrB) [Actinobacillus pleuropneumoniae strain ORG1224]
ATGAGCAAGCAAGGCAAACCTTTTATTTTACATAGCCCGTTTAAACCCTCTGGCGATCAGCCGTCAGCGATTGCCAAATT
GACCGAAGGGCTAAATGACGGATTGGCGCATCAAACGTTACTGGGGGTAACAGGTTCGGGTAAAACCTTTACCATTGCTA
ATGTGATCGCTCAACTCAATCGTCCGGCAATGTTGCTTGCGCCGAATAAAACGCTTGCCGCTCAGCTGTATGCCGAGATG
AAAGCCTTCTTCCCAGAAAATGCGGTGGAATACTTTGTCTCTTACTATGACTATTACCAACCGGAAGCCTATGTGCCGAG
TAGCGATACTTTTATCGAAAAAGATGCGTCGATTAACGAACAAATCGAACAGATGCGACTGTCGGCAACCAAATCATTCC
TTGAACGCCGAGATACTATCGTAGTGGCTTCTGTTTCCGCCATTTATGGTTTGGGGGACGTGGACGCTTATATGCAAATG
ATGTTGCATTTGCAAGTGGGGGCGATTATCGACCAACGAGAGATCCTCGCTCGCCTTGCCGAATTGCAATATACCCGCAA
CGATCAAGCATTTCAGCGTTCGACTTTCCGTGTGCGTGGCGAAGTGATTGATATTTTCCCTGCCGAATCGGATGAAATAG
CGTTACGGGTTGAATTGTTTGACGATGAAATCGAAAGCCTTTCGTTGTTTGATCCGCTTACCGGACATAGCTTGGGCAAA
GTACCTCGCTATACCATTTATCCGAAAACGCACTACGTTACCCCTCGTGAACGCATTTTGAATGCGATTGAGGAAATCAA
GCAAGAATTGGTGGAACGCCGAGAATACTTCATCAAAGAAAATAAATTGTTGGAAGAACAACGTATTACTCAACGCACGC
AATTCGATATTGAAATGATGAATGAGCTGGGCTATTGCTCGGGCATTGAAAACTATTCACGCTATCTGTCGGGCAGAAAA
GAGGGCGAACCGCCTCCGACATTATTCGACTATATGCCGGCGGACGGTTTGCTGATTATTGATGAAAGCCACGTTACCGT
ACCGCAAATCGGCGGTATGTATCGAGGCGACCGAGCAAGAAAAGAAACGCTGGTGCAATACGGGTTCCGCTTGCCTTCAG
CATTGGATAACCGCCCGTTACGTTTTGAAGAATTTGAACGTCTTGCGCCACAGACAATTTATGTTTCGGCAACACCGGGT
AATTATGAATTAGAAAAATCGAATGGTGATGTGGTGGATCAAGTGGTTCGTCCAACGGGATTATTAGACCCGATCATCGA
AGTTCGTCCGGTTGCGACGCAGGTTGATGATGTACTGTCCGAAATTCACAAACGAGTAGCGGTAGATGAACGTGTGCTAA
TTACTACGCTGACCAAAAAAATGGCGGAAGATTTAACCGATTATCTCGATGAACACGGCGTGCGTGTGCGTTATCTGCAT
AGCGATATTGATACGGTTGAACGGGTAGAAATTATTCACGACTTGCGTATGGGAATGTTTGACGTATTGGTCGGCATCAA
CTTATTGCGTGAGGGCTTGGATATGCCGGAAGTGTCGCTGGTGGCGATTTTAGATGCGGATAAAGAAGGCTTTTTACGTT
CCGAACGTTCATTAATTCAGACCATCGGACGTGCCGCTCGAAACCTCAACGGCAAAGCGATTCTCTACGGCGACCGCATT
ACCAATTCTATGCAAAAAGCGATTACCGAAACCGAACGCCGCCGAGAAAAACAGCAAAAATACAACGAAGAACACGGTAT
TACTCCGCAAGCCCTCAATAAGAAAGTAGGCGAATTGCTCGACATCGGACAAACCGACAAGCCGAAACGAGGTAAACAAG
CGGTTAAAATCGAAGAAAAATCTGCAAATACCTATAAACCAAAATCCCGCAAAGAGCTGGAAAAAGAGCTCAAACAGTTA
GAACAACAAATGCGAGATTTTGCTAAGGATCTAGAGTTCGAAAAAGCAGCTGCGGTGAGGGATAAGATTGGGCAGTTGAA
GGCAGTGTTGTTGGAGATCTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(555-596)

Type III restriction enzyme, res subunit (ResIII)

(17-100)

UvrB interaction domain (UvrB_inter)

(162-252)

UvrB/uvrC motif (UVR)

(634-668)

Helicase conserved C-terminal domain (Helicase_C)

(439-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.402

98.366

0.565
  uvrB Streptococcus pneumoniae R6

57.402

98.366

0.565
  uvrB Streptococcus pneumoniae D39

57.402

98.366

0.565

Multiple sequence alignment