Detailed information NTG0271333

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: D0819_RS17465
• Genome accession: NZ_CP031784
• Coordinates: 3355771..3356853 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain HMNig-2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3350771..3361853

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D0819_RS17450 (D0819_17525)	mcsB	3350779..3351870 (+)	1092	WP_021482008.1	protein arginine kinase	-
D0819_RS17455 (D0819_17530)	clpC	3351867..3354299 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
D0819_RS17460 (D0819_17535)	radA/sms	3354391..3355767 (+)	1377	WP_015252992.1	DNA repair protein RadA	Machinery gene
D0819_RS17465 (D0819_17540)	disA	3355771..3356853 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
D0819_RS17470 (D0819_17545)	yacL	3356969..3358069 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
D0819_RS17475 (D0819_17550)	ispD	3358084..3358782 (+)	699	WP_064672086.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
D0819_RS17480 (D0819_17555)	ispF	3358775..3359251 (+)	477	WP_014475594.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
D0819_RS17485 (D0819_17560)	gltX	3359342..3360793 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
D0819_RS17490 (D0819_17570)	cysE	3361095..3361748 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=271333 D0819_RS17465 WP_003225736.1 3355771..3356853(+) (disA) [Bacillus subtilis strain HMNig-2]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=271333 D0819_RS17465 WP_003225736.1 3355771..3356853(+) (disA) [Bacillus subtilis strain HMNig-2]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1