Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SGO_RS10185 Genome accession   NC_009785
Coordinates   2144235..2145155 (-) Length   306 a.a.
NCBI ID   WP_012131044.1    Uniprot ID   A8AZW8
Organism   Streptococcus gordonii str. Challis substr. CH1     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2139235..2150155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGO_RS10155 (SGO_2075) - 2139351..2139965 (+) 615 WP_012131039.1 replication protein -
  SGO_RS10160 - 2139952..2140203 (+) 252 WP_041789829.1 MerR family transcriptional regulator -
  SGO_RS10165 (SGO_2076) - 2140291..2141556 (+) 1266 WP_012131040.1 tyrosine-type recombinase/integrase -
  SGO_RS10170 (SGO_2077) - 2142183..2142938 (-) 756 WP_012131041.1 ABC transporter permease -
  SGO_RS10175 (SGO_2078) - 2142931..2143767 (-) 837 WP_172601495.1 ABC transporter ATP-binding protein -
  SGO_RS10180 (SGO_2079) - 2143764..2143991 (-) 228 WP_041789830.1 hypothetical protein -
  SGO_RS10185 (SGO_2080) comR 2144235..2145155 (-) 921 WP_012131044.1 helix-turn-helix domain-containing protein Regulator
  SGO_RS10190 (SGO_2081) - 2145513..2146205 (+) 693 WP_012131045.1 hypothetical protein -
  SGO_RS10195 (SGO_2082) - 2146221..2146934 (+) 714 WP_012131046.1 hypothetical protein -
  SGO_RS10200 (SGO_2083) - 2147186..2147782 (+) 597 WP_012131047.1 TetR/AcrR family transcriptional regulator -
  SGO_RS10205 (SGO_2084) - 2147779..2148345 (+) 567 WP_012131048.1 NAD(P)H-dependent oxidoreductase -
  SGO_RS10210 (SGO_2085) purB 2148390..2149685 (-) 1296 WP_009443505.1 adenylosuccinate lyase -

Sequence

Protein


Download         Length: 306 a.a.        Molecular weight: 36055.39 Da        Isoelectric Point: 4.5060

>NTDB_id=27119 SGO_RS10185 WP_012131044.1 2144235..2145155(-) (comR) [Streptococcus gordonii str. Challis substr. CH1]
MTIDDKDAELKLKIGNNIRTARLNKNLTQADVCGDESELTIRQLARIENGQVLVSLSKLLFLSQKLNFPIKDIVDIEKME
IPKRYLELKNKLIRSHTYGDEERISILEEMFDEIYENFYEHLPEEEQLLVEVLQVQLDVFSSRDITYGLSLLEEYFQQIL
KKKKYSYNDLLIINLYFLCCATGLEDKTYFEELSKKVLLYIDYSDNDRIYILERILIGILIQVKTEDYLIYTKVLREITE
STNNFQHKPAIYAFEAKYYLKVEESYEKAEQSYNKAIEFANLLNDQVLASNLLKEKELDLIEIPST

Nucleotide


Download         Length: 921 bp        

>NTDB_id=27119 SGO_RS10185 WP_012131044.1 2144235..2145155(-) (comR) [Streptococcus gordonii str. Challis substr. CH1]
ATGACTATTGATGATAAAGATGCTGAATTAAAATTGAAAATCGGTAATAACATCCGTACGGCTCGTCTTAATAAAAACTT
GACTCAAGCGGATGTTTGTGGAGATGAATCTGAATTAACTATTCGTCAACTTGCACGTATTGAAAATGGGCAAGTGTTAG
TATCTCTTTCTAAATTATTGTTTCTATCTCAGAAATTAAATTTTCCCATTAAAGATATAGTAGATATAGAAAAAATGGAA
ATACCCAAACGGTATCTAGAATTAAAAAATAAATTAATACGTTCTCATACTTACGGTGATGAAGAACGTATTAGTATTTT
AGAAGAGATGTTTGATGAAATATATGAGAATTTTTATGAGCATCTCCCAGAAGAAGAACAACTGCTTGTTGAAGTTTTAC
AAGTGCAATTAGATGTTTTTAGTAGTCGAGACATTACTTATGGCTTATCTTTACTCGAGGAGTATTTTCAACAGATTTTA
AAGAAGAAAAAGTATAGCTACAATGACCTCCTAATTATCAATTTGTATTTTCTTTGTTGTGCTACTGGTCTAGAAGATAA
AACTTATTTTGAAGAATTATCTAAAAAAGTTTTATTATATATTGATTATAGTGATAATGATCGTATCTATATACTTGAAA
GAATATTGATAGGAATTTTAATACAAGTAAAAACAGAGGATTACTTAATTTATACCAAAGTTTTACGCGAGATAACTGAA
AGTACAAATAACTTCCAACACAAACCTGCTATTTATGCTTTTGAGGCTAAATATTATTTGAAAGTGGAAGAAAGTTATGA
AAAAGCAGAGCAATCTTATAATAAAGCTATTGAGTTTGCCAACCTGCTTAATGATCAAGTTTTAGCTAGTAATTTGCTTA
AAGAGAAAGAACTTGATTTAATTGAGATTCCATCAACTTAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(82-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AZW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

38.983

96.405

0.376

Multiple sequence alignment