Detailed information NTG0270874

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: D1F63_RS09420
• Genome accession: NZ_CP031770
• Coordinates: 1831788..1832555 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain SASM4-Duke
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1826788..1837555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1F63_RS09405 (D1F63_09405)	hexB	1827306..1829288 (-)	1983	WP_021299132.1	DNA mismatch repair endonuclease MutL	Machinery gene
D1F63_RS09410 (D1F63_09410)	-	1829383..1830534 (-)	1152	WP_003058754.1	site-specific integrase	-
D1F63_RS09415 (D1F63_09415)	-	1830783..1830926 (+)	144	WP_011185066.1	putative holin-like toxin	-
D1F63_RS09420 (D1F63_09420)	irvR	1831788..1832555 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
D1F63_RS09425 (D1F63_09425)	-	1832709..1832915 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
D1F63_RS09430 (D1F63_09430)	-	1832949..1833149 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
D1F63_RS09435 (D1F63_09435)	-	1833170..1833577 (+)	408	WP_002992501.1	hypothetical protein	-
D1F63_RS10130	-	1833590..1833712 (+)	123	WP_011285272.1	hypothetical protein	-
D1F63_RS09440 (D1F63_09440)	-	1833995..1834516 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
D1F63_RS09445 (D1F63_09445)	-	1834764..1834937 (+)	174	WP_000132665.1	hypothetical protein	-
D1F63_RS09450 (D1F63_09450)	-	1835155..1835328 (+)	174	WP_000074663.1	hypothetical protein	-
D1F63_RS09455 (D1F63_09455)	-	1835490..1835921 (+)	432	WP_136302445.1	hypothetical protein	-
D1F63_RS09460 (D1F63_09460)	-	1836023..1836355 (+)	333	WP_011285276.1	hypothetical protein	-
D1F63_RS09465 (D1F63_09465)	-	1836355..1836546 (+)	192	WP_021340709.1	hypothetical protein	-
D1F63_RS09470 (D1F63_09470)	-	1836558..1836887 (+)	330	WP_003058810.1	hypothetical protein	-
D1F63_RS09475 (D1F63_09475)	-	1836890..1837162 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=270874 D1F63_RS09420 WP_003058809.1 1831788..1832555(-) (irvR) [Streptococcus pyogenes strain SASM4-Duke]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=270874 D1F63_RS09420 WP_003058809.1 1831788..1832555(-) (irvR) [Streptococcus pyogenes strain SASM4-Duke]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4