Detailed information NTG0270490

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: DXY22_RS03900
• Genome accession: NZ_CP031693
• Coordinates: 758160..759242 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain SRCM101393
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 753160..764242

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DXY22_RS03885 (DXY22_00760)	mcsB	753168..754259 (+)	1092	WP_003235007.1	protein arginine kinase	-
DXY22_RS03890 (DXY22_00761)	clpC	754256..756688 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
DXY22_RS03895 (DXY22_00762)	radA/sms	756780..758156 (+)	1377	WP_015252992.1	DNA repair protein RadA	Machinery gene
DXY22_RS03900 (DXY22_00763)	disA	758160..759242 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
DXY22_RS03905 (DXY22_00764)	yacL	759358..760458 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
DXY22_RS03910 (DXY22_00765)	ispD	760473..761171 (+)	699	WP_015252991.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
DXY22_RS03915 (DXY22_00766)	ispF	761164..761640 (+)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
DXY22_RS03920 (DXY22_00767)	gltX	761731..763182 (+)	1452	WP_004399675.1	glutamate--tRNA ligase	-
DXY22_RS03925 (DXY22_00768)	cysE	763484..764137 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=270490 DXY22_RS03900 WP_003225736.1 758160..759242(+) (disA) [Bacillus subtilis strain SRCM101393]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=270490 DXY22_RS03900 WP_003225736.1 758160..759242(+) (disA) [Bacillus subtilis strain SRCM101393]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCCATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1