Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   C3438_RS15750 Genome accession   NZ_CP026533
Coordinates   3015613..3016269 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain DKU_NT_04     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3010613..3021269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C3438_RS15725 (C3438_15725) oppF 3011144..3012061 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  C3438_RS15730 (C3438_15730) - 3012168..3013355 (+) 1188 WP_104843255.1 putative glycoside hydrolase -
  C3438_RS15735 (C3438_15735) - 3013473..3014051 (+) 579 WP_104843256.1 GNAT family N-acetyltransferase -
  C3438_RS15740 (C3438_15740) spx 3014230..3014625 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  C3438_RS15745 (C3438_15745) - 3014681..3015337 (-) 657 WP_014417421.1 TerC family protein -
  C3438_RS15750 (C3438_15750) mecA 3015613..3016269 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  C3438_RS15755 (C3438_15755) - 3016420..3017580 (+) 1161 WP_104843257.1 competence protein CoiA family protein -
  C3438_RS15760 (C3438_15760) pepF 3017808..3019637 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  C3438_RS22640 - 3019675..3019842 (-) 168 WP_003155026.1 hypothetical protein -
  C3438_RS15765 (C3438_15765) spxH 3020128..3021030 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=270178 C3438_RS15750 WP_003155032.1 3015613..3016269(+) (mecA) [Bacillus velezensis strain DKU_NT_04]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=270178 C3438_RS15750 WP_003155032.1 3015613..3016269(+) (mecA) [Bacillus velezensis strain DKU_NT_04]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment