Detailed information NTG0269938

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: C3L41_RS01800
• Genome accession: NZ_CP026502
• Coordinates: 358504..360954 (+)
• Length: 816 a.a.
• NCBI ID: WP_014024302.1
• Uniprot ID: F9VBW2
• Organism: Lactococcus garvieae strain JJJN1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 353504..365954

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C3L41_RS01775	-	354412..354924 (+)	513	WP_003134000.1	adenine phosphoribosyltransferase	-
C3L41_RS01780	rpoE	355062..355622 (+)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
C3L41_RS01785	mltG	355728..357443 (+)	1716	WP_014024301.1	endolytic transglycosylase MltG	-
C3L41_RS01790	greA	357468..357941 (+)	474	WP_003134005.1	transcription elongation factor GreA	-
C3L41_RS01795	-	358062..358514 (+)	453	WP_003134006.1	CtsR family transcriptional regulator	-
C3L41_RS01800	clpC	358504..360954 (+)	2451	WP_014024302.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
C3L41_RS01805	raiA	361078..361635 (+)	558	WP_014024303.1	ribosome-associated translation inhibitor RaiA	-
C3L41_RS01810	pflB	361883..364216 (+)	2334	WP_003134012.1	formate C-acetyltransferase	-
C3L41_RS01815	coaE	364448..365053 (+)	606	WP_014024304.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91147.38 Da
• Isoelectric Point: 6.1751

>NTDB_id=269938 C3L41_RS01800 WP_014024302.1 358504..360954(+) (clpC) [Lactococcus garvieae strain JJJN1]
MKFNEKDFTPQVVRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSDI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEKETVAILQGLKEKFEAYHAVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELKLQQAVVALDIVEAQGIEKDIERLTHKIDNFTVSENDNPLV
EESDIYAVVSNLTGIPLQQMTRTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNITVKFTPAALKVIADKGFDPEYGARPLRKALQREIEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=269938 C3L41_RS01800 WP_014024302.1 358504..360954(+) (clpC) [Lactococcus garvieae strain JJJN1]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTCGTTAGAGTGCTCGAGAAGTCTGTCGACTATGCGCATAAGTTTAA
CTACGCTTGGGTAGAAAGCTCGCACCTATTGGCTGCCTTGGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAGATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTAAAGACAAAAAAATCAGACATA
AAGCTTAGCCCAAGAGTCGAAACGATTATTGAGCAAGCCCGAGCATTGGCTCAAAATAACGATAAAAACCGTATTGGAAC
AGAGCATCTCTTGTATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAAACATTAATATCG
TTAACCTCCGTAAAAAGTTAGAGCAAAAAGCATATTTACGAGTGCCAGAACGCCGTAAAGCGGTGACCCCAGCCTCAAAA
AGAAACCTGTCGGGGAAGGTGTCCGAAACAACAACAACACCTACTTTAGATACAGTCTCGACAGATTTGACAAAAGCAGC
GCGTGAAGGAAAGCTTGATCCAATGATTGGGAGAGAGCGTGAAGTCGAACGTCTTATCCATATTTTGAGTCGCCGCACAA
AGAATAATCCCGTTCTTGTTGGTGAACCAGGCGTTGGTAAGTCAGCGATTATTGAAGGCTTTGCAACACGTGTGGCTGCA
GGGAATGTTCCTGTAGGTTTACGCGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTCGTAGCGGGGACGAAGTTCCG
TGGCGAATTTGAAGATCGTTTGACAGCTATTGTGGATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACTATTATTGGTGCTGGGGGAGGCATGGACTCTGTCAATGATGCCTCAAACATTTTAAAACCCGCATTAGCACGT
GGCGAGTTTCAACTTATTGGTGCTACTACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCTCTGGAGCGTCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAAAAGAAACGGTTGCGATTTTACAAGGCTTGAAAGAAAAATTTGAAG
CTTACCATGCGGTTAAATTTGAAGAGGGGGCTTTGGAGCGTGCCGTTAGCTTGAGTAATCGCTACATGCCAAGTCGTCGT
CTGCCAGACAAAGCCATTGATCTTCTTGATGAAGCAGCGGCCAAAGTTAAAATCACGAGTAAAACAAATTACACCAAGCT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAGCTGAAATTACAACAAGCAGTTGTTGCTCTTGATATTGTTGAAGCAC
AAGGAATTGAAAAAGATATTGAAAGATTAACACACAAAATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTC
GAAGAAAGCGATATTTATGCTGTTGTTTCTAACCTTACAGGAATTCCGCTCCAACAAATGACGAGAACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATAAACGTGTGGTCGGACAGGAAGAAGCGATTTCGGCTGTTTCTCGTGCTATAA
GACGTGCGCGTTCAGGTATTGCTGATACGAGACGTCCTCTGGGCTCATTTATGTTCCTTGGTCCGACAGGGGTGGGGAAA
ACAGAGCTTGCTAAAGCTTTAGCGGAAAGTGTCTTTGGGAGTGAAGAGAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCAGGGTATGTAGGTTACGACGAAGGGGGACAATTGACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTTGAAAAAGCCCATCCTGACATTTTCAATATCATGTTG
CAAATTTTGGATGACGGTTTCGTTACAGATACCAAAGGGCGGAAGGTTGATTTCCGAAATACAATCATCATTATGACATC
TAACTTAGGCGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACAGATTATGCAGCCA
TGAAAGCAAGAATCATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTTAACCGTATTGATGAAACCATCGTTTTC
CATTCACTGACTGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCACGTTTGAAAGATCAAAA
TATTACAGTGAAATTTACCCCTGCTGCCTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAGTATGGTGCACGTCCGT
TGCGTAAAGCGCTACAACGGGAGATTGAAGACACGCTCAGTGAGCAATTGCTTGCAGGCGAAATTCATCCGGGGGATACG
ATTTCGATTGGATCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• AAA lid domain (AAA_lid_9) (357-445)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

3D structure

• AlphaFold DB: F9VBW2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.552	99.877	0.705
clpC	Streptococcus thermophilus LMG 18311	49.698	100	0.504
clpC	Streptococcus thermophilus LMD-9	49.698	100	0.504
clpC	Streptococcus pneumoniae TIGR4	49.153	100	0.498
clpC	Streptococcus pneumoniae Rx1	49.031	100	0.496
clpC	Streptococcus pneumoniae D39	49.031	100	0.496
clpC	Streptococcus mutans UA159	47.488	100	0.487
clpC	Bacillus subtilis subsp. subtilis str. 168	48.185	97.917	0.472
clpE	Streptococcus mutans UA159	47.031	78.431	0.369