Detailed information NTG0268418

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DZN22_RS09395
• Genome accession: NZ_CP031637
• Coordinates: 1849218..1849985 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS10786
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1844218..1854985

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZN22_RS09380 (DZN22_09370)	hexB	1844736..1846718 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
DZN22_RS09385 (DZN22_09375)	-	1846813..1847964 (-)	1152	WP_003058754.1	site-specific integrase	-
DZN22_RS10210 (DZN22_09380)	-	1848213..1848356 (+)	144	WP_011185066.1	putative holin-like toxin	-
DZN22_RS09395 (DZN22_09385)	irvR	1849218..1849985 (-)	768	WP_003058809.1	S24 family peptidase	Regulator
DZN22_RS09400 (DZN22_09390)	-	1850139..1850345 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DZN22_RS09405 (DZN22_09395)	-	1850379..1850552 (+)	174	Protein_1761	helix-turn-helix transcriptional regulator	-
DZN22_RS09410 (DZN22_09400)	-	1850600..1851007 (+)	408	WP_002992501.1	hypothetical protein	-
DZN22_RS10215	-	1851020..1851142 (+)	123	WP_011285272.1	hypothetical protein	-
DZN22_RS09415 (DZN22_09405)	-	1851425..1851946 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
DZN22_RS09420 (DZN22_09410)	-	1852194..1852367 (+)	174	WP_000132665.1	hypothetical protein	-
DZN22_RS09425 (DZN22_09415)	-	1852585..1852758 (+)	174	WP_000074663.1	hypothetical protein	-
DZN22_RS09430 (DZN22_09420)	-	1852920..1853351 (+)	432	WP_136302445.1	hypothetical protein	-
DZN22_RS09435 (DZN22_09425)	-	1853453..1853785 (+)	333	WP_011285276.1	hypothetical protein	-
DZN22_RS09440 (DZN22_09430)	-	1853785..1853976 (+)	192	WP_021340709.1	hypothetical protein	-
DZN22_RS09445 (DZN22_09435)	-	1853988..1854317 (+)	330	WP_003058810.1	hypothetical protein	-
DZN22_RS09450 (DZN22_09440)	-	1854320..1854592 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=268418 DZN22_RS09395 WP_003058809.1 1849218..1849985(-) (irvR) [Streptococcus pyogenes strain MGAS10786]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=268418 DZN22_RS09395 WP_003058809.1 1849218..1849985(-) (irvR) [Streptococcus pyogenes strain MGAS10786]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4