Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexB   Type   Machinery gene
Locus tag   DZN63_RS06565 Genome accession   NZ_CP031635
Coordinates   1296192..1299407 (-) Length   1071 a.a.
NCBI ID   WP_011284663.1    Uniprot ID   Q48UB9
Organism   Streptococcus pyogenes strain MGAS11052     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1291192..1304407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DZN63_RS06550 (DZN63_06545) rpsU 1291294..1291470 (-) 177 WP_000048058.1 30S ribosomal protein S21 -
  DZN63_RS06555 (DZN63_06550) - 1291611..1292423 (-) 813 WP_002990394.1 transporter substrate-binding domain-containing protein -
  DZN63_RS06560 (DZN63_06555) rexA 1292563..1296195 (-) 3633 WP_129801703.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  DZN63_RS06565 (DZN63_06560) rexB 1296192..1299407 (-) 3216 WP_011284663.1 ATP-dependent nuclease subunit B Machinery gene
  DZN63_RS06570 (DZN63_06565) - 1299558..1300475 (+) 918 WP_011284662.1 neutral zinc metallopeptidase -
  DZN63_RS06575 (DZN63_06570) - 1300580..1301248 (-) 669 WP_021340733.1 ABC transporter ATP-binding protein -
  DZN63_RS06580 (DZN63_06575) - 1301258..1302334 (-) 1077 WP_002985207.1 ABC transporter permease -
  DZN63_RS06585 (DZN63_06580) - 1302407..1302793 (-) 387 WP_002985209.1 YbgA family protein -
  DZN63_RS06590 (DZN63_06585) - 1302786..1303163 (-) 378 WP_002985212.1 OsmC family protein -

Sequence

Protein


Download         Length: 1071 a.a.        Molecular weight: 124207.12 Da        Isoelectric Point: 6.8336

>NTDB_id=268210 DZN63_RS06565 WP_011284663.1 1296192..1299407(-) (rexB) [Streptococcus pyogenes strain MGAS11052]
MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQH
LDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
QDYNQDSPLQSFARAIKLGLLNNQLSKTVIVIDGFSRFSAEEDYLLSLLNNNCQEVIIGSYVSQKAYQKSFIKGNIYEAS
LHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLY
EGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDD
SDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGASLVDKLILFFKKIRLAENM
QGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFV
YAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVPTVINETFDDLSP
YLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYR
LSTKPLSKEVIEVCFPKGIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFD
NKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQEKNFHLDMGNEILVHGIIDRIDQLS
DGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLAALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKAL
TYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEAD
LDMAQARRLVTLPAKEKKECFLTLMRKESHL

Nucleotide


Download         Length: 3216 bp        

>NTDB_id=268210 DZN63_RS06565 WP_011284663.1 1296192..1299407(-) (rexB) [Streptococcus pyogenes strain MGAS11052]
ATGAAATTAATTTACACAGAGATGAGTTACTCGATGACAGAGATTTTGGTGAATGAAGCACGAAAAGCTGCTGACCAAGG
TTATCGAGTGTTCTATATTGCTCCAAATTCTCTTTCATTTGAAAAGGAAAGAGAAGTCTTAACCTTATTGCCTGAACGAG
GGACTTTTTCGATAATAGTAACCCGGTTCGTTCAAATGTCAAGGTATTTTACAGTTGAGAGCTCTCCTTCTAAGCAACAT
CTAGATGACACGACTTTGGCTATGATTTTTTATCGGGCCTTGATGCAATTAAAACCAGAAGATTTGCCGAGTTATGGTCG
TTTGCAAAATAATTCGGTTTTTATTGAACAACTAGTTGAGTTATATAAGGAATTAAAAAACGCACAATTAAGCGTACATG
ATTTAACAGGATTAGACCATCCTCAAAAACAAGAAGATCTTATTAAAATTATTGAGCTTGCAGAGACGATCATGATTCAG
CAAGATTATAATCAAGATAGTCCTCTACAATCTTTTGCAAGAGCAATTAAGTTAGGACTTTTAAATAACCAACTATCAAA
AACAGTTATTGTTATTGATGGTTTTTCACGTTTTTCAGCTGAAGAGGATTATTTATTATCACTTTTAAATAACAACTGTC
AAGAGGTCATCATTGGCAGTTATGTGAGTCAAAAAGCTTATCAAAAATCTTTTATTAAGGGAAATATCTATGAGGCTAGC
CTTCATTTTTTGCAAGATTTGGCTCAAAAATACCATATCAAGCCGGTATTTGCGACCTCTAATCAAGTGTTTAAACCAGC
CTTTTCACGGCTAACACAATTATTTGAAGCAACTCATGATTTTTCACAAGTAGACTGGCAACTCCAAAAGAATGATCTTG
ATCACTTTAGCCTTTGGCAATGTCATCATCAAAAAGAGGAAATTGAACATGTAGCAAAATCCATTCGGCAAAAGCTATAT
GAAGGTTACCGTTATAAGGATATCTTAGTGTTGCTAGGAGATATGGATGCTTATCAATTACAAATTGGGCCTATCTTTGA
TAAGTTTGAAATCCCCTACTATTTAGGAAAAGCAGAGCCTATGGCTGCCCATCCATTAGTCCAATTTATAGAATCGCTCG
AACGAAGTCAGCGCTATAATTGGCGTCGTGAAGACATTTTAAACATGTTAAAATCAGGACTTTTTGGTTGTTTTGATGAT
AGTGATATTGATCGCTTTGAGGAATATACTCAGTTTGCAGATATTAAAGGATTTACTAAATTTTCAAAGCCTTTTACCAT
TAACTCTTCTAGGCAGTATCCTCTTGACTTTTTAAATGAAATGAGACAAGACATCGTTTTACCTTTGCAAGAATTGTTTA
AGAGTCAAAAACAACTTGGTGCTTCACTTGTTGACAAATTAATACTTTTTTTTAAAAAGATTAGATTAGCTGAGAATATG
CAAGGTTTAGCACAGTCCCAATTAGAGGTGGAAAAAAACGAAGAAGTTTGGAAAAGGTTTACAGATATTTTGACTTCTTT
TCATCATATCTTTGGCCAAGAAAAATTACGGCTATCAGATTGCCTTGCTTTAATCAAAACGGGAATGAAATCAGCTCAGT
ATCGTGTTGTTCCAGCGACATTAGATGTTGTCACTATTAAATCTTATGACCTTGTTCAACCACATTCAAAACCTTTCGTT
TATGCAATTGGTCTAACTCAATCACATTTTCCTAAGCAAATTCACCATTCAGGACTACTTTCTGATCAAGAGCGTGCTAG
AATTAATGAAATAAGAAATTATCGTCATTTTGATATTGCTAGTGCCGAAAATAGTAAAAAAAACCATCAAACTGCGTTAT
CTCTGTTTAATGCTGCTACTAAAGAGTTAGTTCTTAGTGTTCCAACGGTAATCAACGAGACATTCGATGATCTATCTCCT
TATCTTAAAGAATTAATAAGCTTTGGGCTACCTCTTTTGGATAAAGGCAAAAACTATCTATCTTATGATAATAGCGATAT
TGGTAACTATAAAGCTCTCTTGTCACAAATTATTGCTATTAACCGACAAGATCTTATAGAAATGTCAGATCAAGATAAGA
TGTTTTGGACTGTTGTCTTACGTTATCTCAGGAAACAGTTAAGAAAGCAACAGCTAGAGCTACCTACTTCAGATTATCGT
TTATCAACAAAGCCTTTGTCTAAAGAAGTTATCGAGGTATGTTTTCCAAAGGGAATCCCTTTAAAGCTATCTGCAACTGC
TTTAACCGTTTTTTATAATAATCAGTACAACTATTTTTTGAAATATGTTTTGAATTTAAACAAAACAGAATCCATTCATC
CAGATTCCAGAATTCATGGTCAATACTTGCATCGTGTCTTTGAGCGGTTAATGAAAGATCACACGCAAGAACCGTTTGAT
AATAAATTAAAACAAGCAATCTACCATACCAATCAAGAAAGTTTTTTTCAGCAGGTTTACCAAGATAATGCCGAGGCTGA
GTACAGTTTAGCTATACTAGAAGATATTGTTAGATCAACAGCACCTATCTTGCAACTTAACCAAAACATAAAGGTCATTG
ATCAAGAAAAGAACTTTCATCTGGATATGGGAAATGAGATATTAGTCCACGGGATCATTGATCGTATTGACCAGCTGAGC
GACGGTAGCTTGGGCATTGTTGACTATAAATCAAGCGCGAATCAATTTGATATTGGGACCTTTTATAATGGGTTGAGTCC
ACAACTAGTGACTTACCTCGCAGCCTTAAAACAGATCGCACCGCACGATATAAACCAATTATTTGGGGCTATGTACCTTC
ATTTGCAAGATCCTAAATTGGATCTAGTAACATTTAAACAAATTGATAACACATTAGTGGAGAGTATCTATAAAGCGTTG
ACCTATAAAGGTATTTTTTCAGAAGTCGAAAAAGAGCATCTATCTACTGGTGCTTACCAAACCAAAAATGCTCTTTATTC
CAATGACGAATTGGAAACACTTTTAAATTATAACAAGTACCTCTATCTTAAAGCTGCTAAACACATTAAAAAGGGACATT
TTTTGATTAATCCTTATACAAGCGATGGTAAGACAGTTCAAGGAGATCAATTAAAAGCCATTACCCGTTTTGAAGCAGAT
CTTGACATGGCACAGGCAAGGCGACTAGTGACTCTCCCTGCTAAGGAGAAAAAAGAGTGCTTTTTAACATTAATGAGAAA
GGAGAGCCACTTGTGA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(743-1020)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48UB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexB Streptococcus pneumoniae R6

41.155

100

0.413

Multiple sequence alignment