Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   C2842_RS00220 Genome accession   NZ_CP026324
Coordinates   37667..38404 (+) Length   245 a.a.
NCBI ID   WP_000660509.1    Uniprot ID   A0AAC8N035
Organism   Helicobacter pylori strain 26695-dRdM2     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32667..43404
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2842_RS00195 (C2842_00195) panD 34824..35177 (+) 354 WP_000142250.1 aspartate 1-decarboxylase -
  C2842_RS00200 (C2842_00200) - 35180..35473 (+) 294 WP_000347915.1 YbaB/EbfC family nucleoid-associated protein -
  C2842_RS00205 (C2842_00205) - 35473..36477 (+) 1005 WP_000468475.1 PDZ domain-containing protein -
  C2842_RS00210 (C2842_00210) comB6 36485..37540 (+) 1056 WP_000786660.1 P-type conjugative transfer protein TrbL Machinery gene
  C2842_RS08335 (C2842_00215) - 37556..37670 (+) 115 Protein_33 comB7 lipoprotein -
  C2842_RS00220 (C2842_00220) comB8 37667..38404 (+) 738 WP_000660509.1 type IV secretion system protein Machinery gene
  C2842_RS00225 (C2842_00225) comB9 38404..39381 (+) 978 WP_001862530.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  C2842_RS00230 (C2842_00230) comB10 39374..40510 (+) 1137 WP_001045839.1 DNA type IV secretion system protein ComB10 Machinery gene
  C2842_RS00235 (C2842_00235) - 40580..41992 (+) 1413 WP_000694809.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  C2842_RS00240 (C2842_00240) gmd 42034..43179 (+) 1146 WP_000659810.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28567.79 Da        Isoelectric Point: 8.9546

>NTDB_id=268160 C2842_RS00220 WP_000660509.1 37667..38404(+) (comB8) [Helicobacter pylori strain 26695-dRdM2]
MKEKPFNSEQLIYLEELLNHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=268160 C2842_RS00220 WP_000660509.1 37667..38404(+) (comB8) [Helicobacter pylori strain 26695-dRdM2]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAACCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGTATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GTGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTTTTGAACGAAAACAAGTTGGTGTATGAAAAGCGTTATAAAATCGTATTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGATTTAAAATCACCCGTTACAGCATCACTGAAATC
ACTAATAGGGGTGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.98

Multiple sequence alignment