Detailed information NTG0267777

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DZR83_RS08775
• Genome accession: NZ_CP031630
• Coordinates: 1754998..1755765 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS28271
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1749998..1760765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZR83_RS08760 (DZR83_08750)	hexB	1750516..1752498 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
DZR83_RS08765 (DZR83_08755)	-	1752593..1753744 (-)	1152	WP_003058754.1	site-specific integrase	-
DZR83_RS08770 (DZR83_08760)	-	1753993..1754136 (+)	144	WP_011185066.1	putative holin-like toxin	-
DZR83_RS08775 (DZR83_08765)	irvR	1754998..1755765 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
DZR83_RS08780 (DZR83_08770)	-	1755919..1756125 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DZR83_RS08785 (DZR83_08775)	-	1756159..1756359 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
DZR83_RS08790 (DZR83_08780)	-	1756380..1756787 (+)	408	WP_002992501.1	hypothetical protein	-
DZR83_RS09530	-	1756800..1756922 (+)	123	WP_011285272.1	hypothetical protein	-
DZR83_RS08795 (DZR83_08785)	-	1757205..1757726 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
DZR83_RS08800 (DZR83_08790)	-	1757974..1758147 (+)	174	WP_000132665.1	hypothetical protein	-
DZR83_RS08805 (DZR83_08795)	-	1758365..1758538 (+)	174	WP_000074663.1	plasmid mobilization protein	-
DZR83_RS08810 (DZR83_08800)	-	1758700..1759131 (+)	432	WP_136302445.1	hypothetical protein	-
DZR83_RS08815 (DZR83_08805)	-	1759233..1759565 (+)	333	WP_011285276.1	hypothetical protein	-
DZR83_RS08820 (DZR83_08810)	-	1759565..1759756 (+)	192	WP_021340709.1	hypothetical protein	-
DZR83_RS08825 (DZR83_08815)	-	1759768..1760097 (+)	330	WP_003058810.1	hypothetical protein	-
DZR83_RS08830 (DZR83_08820)	-	1760100..1760372 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=267777 DZR83_RS08775 WP_003058809.1 1754998..1755765(-) (irvR) [Streptococcus pyogenes strain MGAS28271]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=267777 DZR83_RS08775 WP_003058809.1 1754998..1755765(-) (irvR) [Streptococcus pyogenes strain MGAS28271]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4