Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   DZR83_RS06240 Genome accession   NZ_CP031630
Coordinates   1227521..1231150 (-) Length   1209 a.a.
NCBI ID   WP_277984781.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS28271     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1222521..1236150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DZR83_RS06215 (DZR83_06215) rpoD 1222700..1223809 (-) 1110 WP_002985187.1 RNA polymerase sigma factor RpoD -
  DZR83_RS06220 (DZR83_06220) dnaG 1223818..1225632 (-) 1815 WP_011284666.1 DNA primase -
  DZR83_RS06225 (DZR83_06225) mscL 1225762..1226124 (+) 363 WP_002990299.1 large conductance mechanosensitive channel protein MscL -
  DZR83_RS06230 (DZR83_06230) rpsU 1226252..1226428 (-) 177 WP_000048058.1 30S ribosomal protein S21 -
  DZR83_RS06235 (DZR83_06235) - 1226569..1227381 (-) 813 WP_002990394.1 transporter substrate-binding domain-containing protein -
  DZR83_RS06240 (DZR83_06240) rexA 1227521..1231150 (-) 3630 WP_277984781.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  DZR83_RS06245 (DZR83_06245) rexB 1231150..1234365 (-) 3216 WP_011284663.1 ATP-dependent nuclease subunit B Machinery gene
  DZR83_RS06250 (DZR83_06250) - 1234516..1235433 (+) 918 WP_011284662.1 neutral zinc metallopeptidase -

Sequence

Protein


Download         Length: 1209 a.a.        Molecular weight: 138910.05 Da        Isoelectric Point: 6.5805

>NTDB_id=267752 DZR83_RS06240 WP_277984781.1 1227521..1231150(-) (rexA) [Streptococcus pyogenes strain MGAS28271]
MSFAPFLSPEAIKHLQENERCSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFT
VKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLGQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVLK
QEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDI
ELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVT
VSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDITHFAIKILEENTDIR
QFYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFR
SQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAKE
IIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYSIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRSP
MFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFND
RFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQF
PYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVA
MTRAEKKVYFIGKASKSKSQDITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRLQ
TPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEPLLEPIGVDIIEKSSRSLSDFTLP
HFSKKVKVEASHIGSALHQLMQVLPLSKPINQQTLLDALREIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYRE
APFAILKVDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLMG
GGKPEIVEV

Nucleotide


Download         Length: 3630 bp        

>NTDB_id=267752 DZR83_RS06240 WP_277984781.1 1227521..1231150(-) (rexA) [Streptococcus pyogenes strain MGAS28271]
ATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTACAAGAAAACGAAAGGTGCAGTGATCAGTCTCAAAA
ACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAAAAA
CCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTTACT
GTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCAAAT
GAAAGTTTATTTAACAGAACAATTGCAATCTCTTGGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAGTAG
TAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTAAAG
CAAGAGGTGTTTAGCAAACTCTTTAGTGAGTTTATGAATCAAAAAGAGGCACCGGTGTTTAGGGCTCTTGTGAAAAATTT
TTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAAATC
CAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGGCTTGAAGATATCCCGGATCATGATATT
GAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCTGAC
TAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATTTTA
AATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGGCCTTATACCATCTGGGAATGATGTTACA
GTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAATTAAAACAATTTAGGCATTTAGAAACAATTTTAAT
GTATCAGAAAGACTGTTTTCCCTTATTGGAACAGTTACAAGATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTGTCA
AAATACAAGAAAGTGCTTTTGAATTTTCAGATATTACACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATTCGC
CAATTCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCTGAC
CTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATCCTC
AGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAACCTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTTCGT
AGCCAATCAGAGGTGTTAAATGTCAGCAATGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATACGA
TGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTATATA
ATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGGTATTTCATTTAGTGAGGTTACAATTGTTGCCAAAGAA
ATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGACATTACGTTACTCGTTTCTTCAAGAACAAGAAATGATAT
CATTTCTCATACATTCAATCAATATAGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTGAAG
TGATGGTTATGTTAGATACATTACGCACCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCACCG
ATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATATGA
CAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTCATCCTGAATTGATTCACGATACCTTGCTTGGCAAGTTAAATATTT
TTTTAAAGACGTTGAAAAGTTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTTAATGAT
CGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACGTGC
TAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAAATG
ACTTAGCAGATGTGGAAGTGGCTGCTCCTAAACAAGCTGTTAATTTAATGACCATTCACAAGTCTAAAGGTTTACAATTT
CCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACAGATATTCATAAATCATTTATTCTGAATCGGCAGCA
CGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCATGG
AAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTAGCAACTTTATCAGAACAAATGCGCTTATTGTATGTTGCT
ATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGATATCACAGATCCTAAAAA
GTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATATAT
TTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTTCAA
ACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTTAGA
AGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACGCCTAGCCAACTTAAGGCAG
CTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTGCCA
CATTTTTCAAAAAAAGTAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTTGTC
AAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGAAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTGATC
TCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGAGAA
GCACCATTTGCTATTTTAAAAGTTGACCCTATTAGTCAAGAAGAATATGTCCTACGTGGTATTATAGATGCCTACTTTTT
GTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACCAAC
AACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATGGGA
GGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(29-463)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1046-1196)

UvrD-like helicase C-terminal domain (UvrD_C)

(473-891)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

48.208

100

0.49