Detailed information NTG0267592

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DZS39_RS08800
• Genome accession: NZ_CP031628
• Coordinates: 1763769..1764536 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS28330
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1758769..1769536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZS39_RS08785 (DZS39_08775)	hexB	1759287..1761269 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
DZS39_RS08790 (DZS39_08780)	-	1761364..1762515 (-)	1152	WP_003058754.1	site-specific integrase	-
DZS39_RS09585 (DZS39_08785)	-	1762764..1762907 (+)	144	WP_011185066.1	putative holin-like toxin	-
DZS39_RS08800 (DZS39_08790)	irvR	1763769..1764536 (-)	768	WP_003058809.1	S24 family peptidase	Regulator
DZS39_RS08805 (DZS39_08795)	-	1764690..1764896 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DZS39_RS08810 (DZS39_08800)	-	1764930..1765103 (+)	174	Protein_1637	helix-turn-helix transcriptional regulator	-
DZS39_RS08815 (DZS39_08805)	-	1765151..1765558 (+)	408	WP_002992501.1	hypothetical protein	-
DZS39_RS09590	-	1765571..1765693 (+)	123	WP_011285272.1	hypothetical protein	-
DZS39_RS08820 (DZS39_08810)	-	1765976..1766497 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
DZS39_RS08825 (DZS39_08815)	-	1766745..1766918 (+)	174	WP_000132665.1	hypothetical protein	-
DZS39_RS08830 (DZS39_08820)	-	1767136..1767309 (+)	174	WP_000074663.1	hypothetical protein	-
DZS39_RS08835 (DZS39_08825)	-	1767471..1767902 (+)	432	WP_136302445.1	hypothetical protein	-
DZS39_RS08840 (DZS39_08830)	-	1768004..1768336 (+)	333	WP_011285276.1	hypothetical protein	-
DZS39_RS08845 (DZS39_08835)	-	1768336..1768527 (+)	192	WP_021340709.1	hypothetical protein	-
DZS39_RS08850 (DZS39_08840)	-	1768539..1768868 (+)	330	WP_003058810.1	hypothetical protein	-
DZS39_RS08855 (DZS39_08845)	-	1768871..1769143 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=267592 DZS39_RS08800 WP_003058809.1 1763769..1764536(-) (irvR) [Streptococcus pyogenes strain MGAS28330]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=267592 DZS39_RS08800 WP_003058809.1 1763769..1764536(-) (irvR) [Streptococcus pyogenes strain MGAS28330]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4