Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   C2E46_RS00735 Genome accession   NZ_CP026082
Coordinates   107425..107904 (+) Length   159 a.a.
NCBI ID   WP_001872860.1    Uniprot ID   A0AB74H8K8
Organism   Streptococcus agalactiae strain YZ1605     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 102425..112904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS00710 (C2E46_00715) - 102611..103051 (+) 441 WP_000716196.1 hypothetical protein -
  C2E46_RS00715 (C2E46_00720) - 103044..103388 (+) 345 WP_000073534.1 hypothetical protein -
  C2E46_RS00720 (C2E46_00725) - 104178..104729 (+) 552 WP_000161847.1 nucleotidyltransferase family protein -
  C2E46_RS00725 (C2E46_00730) - 104949..105368 (+) 420 WP_000784700.1 YjdF family protein -
  C2E46_RS00730 (C2E46_00735) ltrA 105932..107209 (+) 1278 WP_001292556.1 group II intron reverse transcriptase/maturase -
  C2E46_RS00735 (C2E46_00740) comX/sigX 107425..107904 (+) 480 WP_001872860.1 sigma-70 family RNA polymerase sigma factor Regulator
  C2E46_RS00740 (C2E46_00745) - 108026..108718 (+) 693 WP_000049272.1 histidine phosphatase family protein -
  C2E46_RS00745 (C2E46_00750) - 108715..109467 (+) 753 WP_000739664.1 M15 family metallopeptidase -
  C2E46_RS00750 (C2E46_00755) - 109464..110039 (+) 576 WP_001231505.1 glycoside hydrolase family 73 protein -
  C2E46_RS00755 (C2E46_00760) hrcA 110182..111216 (+) 1035 WP_161501766.1 heat-inducible transcriptional repressor HrcA -
  C2E46_RS00760 (C2E46_00765) grpE 111219..111791 (+) 573 WP_001872862.1 nucleotide exchange factor GrpE -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19417.25 Da        Isoelectric Point: 6.2639

>NTDB_id=266873 C2E46_RS00735 WP_001872860.1 107425..107904(+) (comX/sigX) [Streptococcus agalactiae strain YZ1605]
MRDFEELFDKVKPIVMKLRRNYFVQLWEYDDWIQEGRIVLFRLLEEHPYLLDNEGKLFIYFKTKFSNYLNDVLRHQDCQK
RQFNKMPYEEISEVSHYVKSKGLVLDDYIAYRDTLTKVEETLSDIDKEKFEKLISGERFAGKKQFIRDIQPFFNAFKAD

Nucleotide


Download         Length: 480 bp        

>NTDB_id=266873 C2E46_RS00735 WP_001872860.1 107425..107904(+) (comX/sigX) [Streptococcus agalactiae strain YZ1605]
TTGAGAGATTTTGAGGAGTTGTTTGATAAAGTAAAGCCAATCGTAATGAAGCTGAGAAGAAATTATTTTGTTCAACTTTG
GGAATATGATGATTGGATTCAAGAAGGGCGTATTGTACTTTTTAGGTTGCTTGAAGAACATCCGTATTTATTGGATAATG
AAGGCAAACTATTCATTTACTTTAAAACAAAATTTTCAAATTATTTAAACGATGTATTAAGACATCAAGATTGTCAAAAG
CGACAATTTAATAAAATGCCTTATGAAGAAATCAGTGAAGTTAGTCACTATGTTAAGAGTAAAGGACTAGTTTTAGATGA
CTATATTGCTTATCGTGATACTTTAACAAAAGTGGAAGAAACTTTGTCAGATATTGATAAAGAAAAATTTGAAAAACTGA
TTAGTGGTGAACGTTTCGCGGGGAAGAAACAATTCATACGAGATATTCAACCTTTTTTCAATGCTTTTAAAGCGGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

57.325

98.742

0.566
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

52.349

93.711

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

52.349

93.711

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

52.349

93.711

0.491
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

52.349

93.711

0.491
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

52

94.34

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

52

94.34

0.491
  comX/sigX Streptococcus mutans UA159

49.677

97.484

0.484
  comX Streptococcus sobrinus strain NIDR 6715-7

43.59

98.113

0.428
  comX/sigX Streptococcus suis D9

43.226

97.484

0.421
  comX/sigX Streptococcus suis isolate S10

43.226

97.484

0.421
  comX/sigX Streptococcus suis P1/7

43.226

97.484

0.421
  comX Streptococcus thermophilus LMD-9

42.177

92.453

0.39
  comX Streptococcus thermophilus LMG 18311

42.177

92.453

0.39
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

39.869

96.226

0.384
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

39.869

96.226

0.384
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

39.869

96.226

0.384
  comX/comX2 Streptococcus pneumoniae Rx1

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae TIGR4

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae TIGR4

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae Rx1

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae D39

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae D39

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae R6

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae R6

40.397

94.969

0.384
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

39.216

96.226

0.377
  comX Streptococcus salivarius SK126

40.816

92.453

0.377
  comX/sigX Streptococcus salivarius strain HSISS4

40.816

92.453

0.377
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

38.562

96.226

0.371

Multiple sequence alignment