Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | RK67_RS04030 | Genome accession | NZ_CP026079 |
| Coordinates | 808379..810007 (+) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain FDAARGOS_9 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 771503..815228 | 808379..810007 | within | 0 |
| SCCmec | 807008..828373 | 808379..810007 | within | 0 |
Gene organization within MGE regions
Location: 771503..828373
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RK67_RS03860 (RK67_003860) | - | 771503..774655 (-) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
| RK67_RS03865 (RK67_003865) | - | 774922..775524 (-) | 603 | WP_000908956.1 | hypothetical protein | - |
| RK67_RS03870 (RK67_003870) | - | 775732..776028 (-) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| RK67_RS03875 (RK67_003875) | - | 776077..776280 (-) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| RK67_RS03880 (RK67_003880) | - | 776589..777575 (+) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| RK67_RS14850 | - | 777761..777975 (+) | 215 | Protein_728 | universal stress protein | - |
| RK67_RS03895 (RK67_003895) | sqr | 778242..779435 (-) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| RK67_RS03900 (RK67_003900) | cstB | 779454..780788 (-) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| RK67_RS03905 (RK67_003905) | cstA | 780819..781883 (-) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| RK67_RS03910 (RK67_003910) | cstR | 782020..782280 (+) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| RK67_RS03915 (RK67_003915) | - | 782280..783035 (+) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| RK67_RS03920 (RK67_003920) | - | 783133..783221 (+) | 89 | Protein_734 | hypothetical protein | - |
| RK67_RS03925 (RK67_003925) | - | 783526..783881 (+) | 356 | Protein_735 | tRNA-dihydrouridine synthase | - |
| RK67_RS03930 (RK67_003930) | - | 783979..785724 (-) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| RK67_RS03935 (RK67_003935) | - | 785871..785963 (-) | 93 | WP_001790000.1 | hypothetical protein | - |
| RK67_RS03940 (RK67_003940) | - | 785927..786061 (+) | 135 | WP_001790628.1 | hypothetical protein | - |
| RK67_RS03945 (RK67_003945) | - | 786311..787819 (-) | 1509 | WP_001001347.1 | protein kinase | - |
| RK67_RS03950 (RK67_003950) | - | 787934..788560 (+) | 627 | WP_001176969.1 | hypothetical protein | - |
| RK67_RS03960 (RK67_003960) | - | 789679..790575 (+) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| RK67_RS03965 (RK67_003965) | - | 790585..791454 (+) | 870 | WP_000626133.1 | hypothetical protein | - |
| RK67_RS03970 (RK67_003970) | - | 791999..792556 (-) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| RK67_RS03975 (RK67_003975) | - | 792572..794593 (-) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| RK67_RS03980 (RK67_003980) | kdpA | 794612..796288 (-) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| RK67_RS14855 (RK67_003985) | kdpF | 796309..796389 (-) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| RK67_RS03990 (RK67_003990) | - | 796556..799225 (+) | 2670 | Protein_747 | sensor histidine kinase KdpD | - |
| RK67_RS03995 (RK67_003995) | - | 799200..799895 (+) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| RK67_RS04000 (RK67_004000) | - | 800617..801543 (+) | 927 | Protein_749 | YfcC family protein | - |
| RK67_RS14800 | - | 801750..801884 (-) | 135 | WP_001792216.1 | hypothetical protein | - |
| RK67_RS04005 (RK67_004005) | - | 802054..803195 (+) | 1142 | Protein_751 | IS3-like element ISSau4 family transposase | - |
| RK67_RS04010 (RK67_004010) | - | 803446..804492 (+) | 1047 | WP_001060127.1 | hypothetical protein | - |
| RK67_RS04015 (RK67_004015) | - | 804685..804981 (+) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| RK67_RS04020 (RK67_004020) | - | 804981..806774 (+) | 1794 | WP_000195100.1 | DUF927 domain-containing protein | - |
| RK67_RS04025 (RK67_004025) | ccrA | 807008..808357 (+) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| RK67_RS04030 (RK67_004030) | ccrB | 808379..810007 (+) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| RK67_RS04035 (RK67_004035) | - | 810525..810875 (+) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| RK67_RS04040 (RK67_004040) | - | 810962..811273 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| RK67_RS04045 (RK67_004045) | - | 811291..811797 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| RK67_RS04050 (RK67_004050) | - | 811818..812135 (+) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| RK67_RS04055 (RK67_004055) | - | 812254..813339 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| RK67_RS04060 (RK67_004060) | - | 813336..815228 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| RK67_RS04065 (RK67_004065) | - | 815235..815612 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| RK67_RS04070 (RK67_004070) | - | 815763..816545 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| RK67_RS04075 (RK67_004075) | erm(A) | 816671..817402 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| RK67_RS04085 (RK67_004085) | - | 817936..818598 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| RK67_RS04095 (RK67_004095) | - | 818943..819581 (-) | 639 | Protein_767 | sulfite exporter TauE/SafE family protein | - |
| RK67_RS04100 (RK67_004100) | cstR | 819581..819841 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| RK67_RS04105 (RK67_004105) | - | 819977..821041 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| RK67_RS04110 (RK67_004110) | cstB | 821074..822408 (+) | 1335 | Protein_770 | persulfide dioxygenase-sulfurtransferase CstB | - |
| RK67_RS04120 (RK67_004120) | - | 822522..823652 (-) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| RK67_RS04125 | psm-mec | 823986..824054 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| RK67_RS04130 (RK67_004130) | mecI | 824139..824510 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| RK67_RS04135 (RK67_004135) | mecR1 | 824510..826267 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| RK67_RS04140 (RK67_004140) | mecA | 826364..828373 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=266797 RK67_RS04030 WP_001186602.1 808379..810007(+) (ccrB) [Staphylococcus aureus strain FDAARGOS_9]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=266797 RK67_RS04030 WP_001186602.1 808379..810007(+) (ccrB) [Staphylococcus aureus strain FDAARGOS_9]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |