Detailed information NTG0266765

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DZ066_RS09520
• Genome accession: NZ_CP031619
• Coordinates: 1858823..1859590 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS29284
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1853823..1864590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZ066_RS09505 (DZ066_09490)	hexB	1854341..1856323 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
DZ066_RS09510 (DZ066_09495)	-	1856418..1857569 (-)	1152	WP_003058754.1	site-specific integrase	-
DZ066_RS10330 (DZ066_09500)	-	1857818..1857961 (+)	144	WP_011185066.1	putative holin-like toxin	-
DZ066_RS09520 (DZ066_09505)	irvR	1858823..1859590 (-)	768	WP_003058809.1	S24 family peptidase	Regulator
DZ066_RS09525 (DZ066_09510)	-	1859744..1859950 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DZ066_RS09530 (DZ066_09515)	-	1859984..1860157 (+)	174	Protein_1780	helix-turn-helix transcriptional regulator	-
DZ066_RS09535 (DZ066_09520)	-	1860205..1860612 (+)	408	WP_002992501.1	hypothetical protein	-
DZ066_RS10335	-	1860625..1860747 (+)	123	WP_011285272.1	hypothetical protein	-
DZ066_RS09540 (DZ066_09525)	-	1861030..1861551 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
DZ066_RS09545 (DZ066_09530)	-	1861799..1861972 (+)	174	WP_000132665.1	hypothetical protein	-
DZ066_RS09550 (DZ066_09535)	-	1862134..1862565 (+)	432	WP_136302445.1	hypothetical protein	-
DZ066_RS09555 (DZ066_09540)	-	1862667..1862999 (+)	333	WP_011285276.1	hypothetical protein	-
DZ066_RS09560 (DZ066_09545)	-	1862999..1863190 (+)	192	WP_021340709.1	hypothetical protein	-
DZ066_RS09565 (DZ066_09550)	-	1863202..1863531 (+)	330	WP_003058810.1	hypothetical protein	-
DZ066_RS09570 (DZ066_09555)	-	1863534..1863806 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=266765 DZ066_RS09520 WP_003058809.1 1858823..1859590(-) (irvR) [Streptococcus pyogenes strain MGAS29284]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=266765 DZ066_RS09520 WP_003058809.1 1858823..1859590(-) (irvR) [Streptococcus pyogenes strain MGAS29284]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4