Detailed information NTG0266691

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RL05_RS07155
• Genome accession: NZ_CP026074
• Coordinates: 1252834..1253721 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain FDAARGOS_47
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1247834..1258721

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RL05_RS07120 (RL05_007120)	-	1247853..1247945 (+)	93	WP_010956583.1	hypothetical protein	-
RL05_RS07125 (RL05_007125)	-	1248053..1248550 (-)	498	WP_001065268.1	glutathione peroxidase	-
RL05_RS07130 (RL05_007130)	-	1248560..1248820 (-)	261	WP_001791974.1	hypothetical protein	-
RL05_RS07140 (RL05_007140)	-	1249202..1249315 (-)	114	Protein_1323	hypothetical protein	-
RL05_RS07145 (RL05_007145)	-	1249974..1251974 (-)	2001	WP_000776751.1	ABC transporter permease	-
RL05_RS07150 (RL05_007150)	-	1251971..1252726 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RL05_RS07155 (RL05_007155)	braS	1252834..1253721 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RL05_RS07160 (RL05_007160)	braR	1253732..1254397 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RL05_RS07165 (RL05_007165)	-	1254423..1254623 (-)	201	WP_000604730.1	hypothetical protein	-
RL05_RS07170 (RL05_007170)	-	1254821..1256245 (+)	1425	WP_000953755.1	alkaline phosphatase	-
RL05_RS15575 (RL05_007175)	-	1256305..1256406 (-)	102	WP_000731976.1	SE2200 family small protein	-
RL05_RS07180 (RL05_007180)	-	1256528..1256983 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RL05_RS07185 (RL05_007185)	-	1257228..1257989 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=266691 RL05_RS07155 WP_000143425.1 1252834..1253721(-) (braS) [Staphylococcus aureus strain FDAARGOS_47]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=266691 RL05_RS07155 WP_000143425.1 1252834..1253721(-) (braS) [Staphylococcus aureus strain FDAARGOS_47]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1