Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   DZ106_RS06565 Genome accession   NZ_CP031618
Coordinates   1291410..1295042 (-) Length   1210 a.a.
NCBI ID   WP_129801703.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS29326     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1286410..1300042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DZ106_RS06540 (DZ106_06535) rpoD 1286589..1287698 (-) 1110 WP_002985187.1 RNA polymerase sigma factor RpoD -
  DZ106_RS06545 (DZ106_06540) dnaG 1287707..1289521 (-) 1815 WP_011284666.1 DNA primase -
  DZ106_RS06550 (DZ106_06545) mscL 1289651..1290013 (+) 363 WP_002990299.1 large conductance mechanosensitive channel protein MscL -
  DZ106_RS06555 (DZ106_06550) rpsU 1290141..1290317 (-) 177 WP_000048058.1 30S ribosomal protein S21 -
  DZ106_RS06560 (DZ106_06555) - 1290458..1291270 (-) 813 WP_002990394.1 transporter substrate-binding domain-containing protein -
  DZ106_RS06565 (DZ106_06560) rexA 1291410..1295042 (-) 3633 WP_129801703.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  DZ106_RS06570 (DZ106_06565) rexB 1295039..1298254 (-) 3216 WP_011284663.1 ATP-dependent nuclease subunit B Machinery gene
  DZ106_RS06575 (DZ106_06570) - 1298405..1299322 (+) 918 WP_011284662.1 neutral zinc metallopeptidase -

Sequence

Protein


Download         Length: 1210 a.a.        Molecular weight: 139005.24 Da        Isoelectric Point: 6.6425

>NTDB_id=266647 DZ106_RS06565 WP_129801703.1 1291410..1295042(-) (rexA) [Streptococcus pyogenes strain MGAS29326]
MISFAPFLSPEAIKHLQENERCSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTF
TVKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLGQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVL
KQEVFSKLFSEFMKQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHD
IELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDV
TVSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDITHFAIKILEENTDI
RQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENF
RSQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAK
EIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYSIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRS
PMFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFN
DRFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQ
FPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYV
AMTRAEKKVYFIGKASKSKSQDITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKVAYEPLLEPIGVDIIEKSSRSLSDFTL
PHFSKKVKVEASHIGSALHQLMQVLPLSKPINQQTLLDALREIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYR
EAPFAILKVDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLM
GGGKPEIVEV

Nucleotide


Download         Length: 3633 bp        

>NTDB_id=266647 DZ106_RS06565 WP_129801703.1 1291410..1295042(-) (rexA) [Streptococcus pyogenes strain MGAS29326]
GTGATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTACAAGAAAACGAAAGGTGCAGTGATCAGTCTCA
AAAACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAA
AAACCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTT
ACTGTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCA
AATGAAAGTTTATTTAACAGAACAATTGCAATCTCTTGGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAG
TAGTAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTA
AAGCAAGAGGTGTTTAGCAAACTCTTTAGTGAGTTTATGAAGCAAAAAGAGGCACCGGTGTTTAGGGCTCTTGTGAAAAA
TTTTTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAA
ATCCAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGGCTTGAAGATATCCCGGATCATGAT
ATTGAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCT
GACTAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATT
TTAAATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGGCCTTATACCATCTGGGAATGATGTT
ACAGTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAATTAAAACAATTTAGGCATTTAGAAACAATTTT
AATGTATCAGAAAGACTGTTTTCCCTTATTGGAACAGTTACAAGATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTG
TCAAAATACAAGAAAGTGCTTTTGAATTTTCAGATATTACACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATT
CGCCAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCT
GACCTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATC
CTCAGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAACCTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTT
CGTAGCCAATCAGAGGTGTTAAATGTCAGCAATGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATA
CGATGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTAT
ATAATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGGTATTTCATTTAGTGAGGTTACAATTGTTGCCAAA
GAAATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGACATTACGTTACTCGTTTCTTCAAGAACAAGAAATGA
TATCATTTCTCATACATTCAATCAATATAGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTG
AAGTGATGGTTATGTTAGATACATTACGCACCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCA
CCGATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATA
TGACAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTCATCCTGAATTGATTCACGATACCTTGCTTGGCAAGTTAAATA
TTTTTTTAAAGACGTTGAAAAGTTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTTAAT
GATCGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACG
TGCTAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAA
ATGACTTAGCAGATGTGGAAGTGGCTGCTCCTAAACAAGCTGTTAATTTAATGACCATTCACAAGTCTAAAGGTTTACAA
TTTCCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACAGATATTCATAAATCATTTATTCTGAATCGGCA
GCACGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCA
TGGAAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTAGCAACTTTATCAGAACAAATGCGCTTATTGTATGTT
GCTATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGATATCACAGATCCTAA
AAAGTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATA
TATTTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTT
CAAACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTT
AGAAGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACGCCTAGCCAACTTAAGG
TAGCTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTG
CCACATTTTTCAAAAAAAGTAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTT
GTCAAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGAAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTG
ATCTCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGA
GAAGCACCATTTGCTATTTTAAAAGTTGACCCTATTAGTCAAGAAGAATATGTCCTACGTGGTATTATAGATGCCTACTT
TTTGTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACC
AACAACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATG
GGAGGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(30-464)

UvrD-like helicase C-terminal domain (UvrD_C)

(474-892)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1047-1197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

48.366

100

0.489