Detailed information NTG0266626

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RL00_RS00835
• Genome accession: NZ_CP026073
• Coordinates: 134117..135160 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_42
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 129117..140160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RL00_RS00795 (RL00_000795)	-	129483..129594 (+)	112	Protein_151	hypothetical protein	-
RL00_RS00800 (RL00_000800)	-	129623..130036 (+)	414	WP_001837236.1	hypothetical protein	-
RL00_RS00810 (RL00_000810)	-	130526..131512 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
RL00_RS00820 (RL00_000820)	map	132043..132801 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RL00_RS00825 (RL00_000825)	-	133018..133404 (+)	387	WP_001110179.1	hypothetical protein	-
RL00_RS00830 (RL00_000830)	liaF	133419..134120 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RL00_RS00835 (RL00_000835)	vraS	134117..135160 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RL00_RS00840 (RL00_000840)	vraR	135150..135779 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RL00_RS00845 (RL00_000845)	-	135891..137102 (-)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
RL00_RS00850 (RL00_000850)	-	137380..137655 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
RL00_RS00855 (RL00_000855)	-	137662..138126 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RL00_RS00860 (RL00_000860)	-	138273..138473 (+)	201	WP_000180460.1	DUF1128 family protein	-
RL00_RS00865 (RL00_000865)	-	138476..139732 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=266626 RL00_RS00835 WP_001017131.1 134117..135160(+) (vraS) [Staphylococcus aureus strain FDAARGOS_42]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=266626 RL00_RS00835 WP_001017131.1 134117..135160(+) (vraS) [Staphylococcus aureus strain FDAARGOS_42]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1