Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RK93_RS12275 Genome accession   NZ_CP026072
Coordinates   2370313..2371029 (-) Length   238 a.a.
NCBI ID   WP_000688490.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FDAARGOS_35     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2365313..2376029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RK93_RS12255 (RK93_012255) - 2366407..2367357 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  RK93_RS12260 (RK93_012260) - 2367506..2368990 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  RK93_RS12265 (RK93_012265) - 2368987..2369946 (+) 960 WP_001253312.1 carbohydrate kinase -
  RK93_RS12270 (RK93_012270) - 2370134..2370241 (-) 108 WP_001790167.1 hypothetical protein -
  RK93_RS12275 (RK93_012275) agrA 2370313..2371029 (-) 717 WP_000688490.1 LytTR family DNA-binding domain-containing protein Regulator
  RK93_RS12280 (RK93_012280) - 2371048..2372340 (-) 1293 WP_001554031.1 GHKL domain-containing protein -
  RK93_RS12285 (RK93_012285) - 2372365..2372505 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  RK93_RS12290 (RK93_012290) agrB 2372502..2373071 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  RK93_RS16000 hld 2373361..2373441 (+) 81 WP_000046022.1 delta-hemolysin -
  RK93_RS12300 (RK93_012300) - 2374038..2374823 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  RK93_RS12305 (RK93_012305) - 2375184..2375810 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27915.94 Da        Isoelectric Point: 6.0927

>NTDB_id=266605 RK93_RS12275 WP_000688490.1 2370313..2371029(-) (agrA) [Staphylococcus aureus strain FDAARGOS_35]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESPTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=266605 RK93_RS12275 WP_000688490.1 2370313..2371029(-) (agrA) [Staphylococcus aureus strain FDAARGOS_35]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCACCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment