Detailed information NTG0266601

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK93_RS08940
• Genome accession: NZ_CP026072
• Coordinates: 1748964..1749851 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_35
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1743964..1754851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK93_RS08910 (RK93_008910)	-	1744696..1745457 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
RK93_RS08915 (RK93_008915)	-	1745702..1746157 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK93_RS16035 (RK93_008920)	-	1746279..1746380 (+)	102	WP_000731972.1	SE2200 family small protein	-
RK93_RS08925 (RK93_008925)	-	1746440..1747864 (-)	1425	WP_000953744.1	alkaline phosphatase	-
RK93_RS08930 (RK93_008930)	-	1748062..1748262 (+)	201	WP_000604728.1	hypothetical protein	-
RK93_RS08935 (RK93_008935)	braR	1748288..1748953 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK93_RS08940 (RK93_008940)	braS	1748964..1749851 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK93_RS08945 (RK93_008945)	-	1749959..1750714 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK93_RS08950 (RK93_008950)	-	1750711..1752711 (+)	2001	WP_000776751.1	ABC transporter permease	-
RK93_RS08955 (RK93_008955)	-	1753370..1753483 (+)	114	WP_011447078.1	hypothetical protein	-
RK93_RS08965 (RK93_008965)	-	1753865..1754125 (+)	261	WP_001789910.1	hypothetical protein	-
RK93_RS08970 (RK93_008970)	-	1754135..1754632 (+)	498	WP_001065268.1	glutathione peroxidase	-
RK93_RS08975 (RK93_008975)	-	1754740..1754832 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=266601 RK93_RS08940 WP_000143419.1 1748964..1749851(+) (braS) [Staphylococcus aureus strain FDAARGOS_35]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=266601 RK93_RS08940 WP_000143419.1 1748964..1749851(+) (braS) [Staphylococcus aureus strain FDAARGOS_35]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997