Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   STER_RS03195 Genome accession   NC_008532
Coordinates   588005..590263 (-) Length   752 a.a.
NCBI ID   WP_011680918.1    Uniprot ID   -
Organism   Streptococcus thermophilus LMD-9     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 583005..595263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STER_RS11675 (STER_0642) - 583401..583637 (+) 237 WP_011680913.1 hypothetical protein -
  STER_RS11680 (STER_0643) - 583687..584022 (+) 336 Protein_551 DUF3862 domain-containing protein -
  STER_RS03160 - 584234..584776 (+) 543 WP_041827661.1 TVP38/TMEM64 family protein -
  STER_RS03165 (STER_0644) - 584754..585989 (+) 1236 WP_011680915.1 aminoacyltransferase -
  STER_RS10170 (STER_0645) - 586088..587051 (+) 964 Protein_554 Gfo/Idh/MocA family protein -
  STER_RS03185 (STER_0646) - 587092..587394 (-) 303 WP_011680916.1 DUF1827 family protein -
  STER_RS03190 (STER_0647) - 587404..587862 (-) 459 WP_011680917.1 NUDIX hydrolase -
  STER_RS03195 (STER_0648) clpE 588005..590263 (-) 2259 WP_011680918.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  STER_RS03200 (STER_0649) argF 590504..591484 (+) 981 WP_011680919.1 ornithine carbamoyltransferase -
  STER_RS03205 (STER_0650) - 591553..591783 (+) 231 WP_011225686.1 DUF1797 family protein -
  STER_RS03210 (STER_0651) - 592053..592732 (+) 680 Protein_560 amino acid ABC transporter permease -
  STER_RS03215 (STER_0652) - 592732..593466 (+) 735 WP_011225688.1 amino acid ABC transporter ATP-binding protein -
  STER_RS03220 (STER_0653) - 593640..594116 (+) 477 WP_011680921.1 ferrous iron transport protein A -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83745.90 Da        Isoelectric Point: 5.2102

>NTDB_id=26657 STER_RS03195 WP_011680918.1 588005..590263(-) (clpE) [Streptococcus thermophilus LMD-9]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIIKSDPENPLNQFNQAGGSNFFDDFFSDLNNFRSSSGDLPNTPPTQ
EGGNRGNGGPGRPGGPRQQAPQQPQGLLEEYGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAA
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQQQTI
KDQDMPIITEKHIEAIVEQKTNIPIGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVINHLGDFFSPEFMNRFDGIIE
FSALSKENLLTIVDLMLDGVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLKNPNEKDL
KAVMTSKGHITIKSAKKTEKTSQKTEALKEVN

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=26657 STER_RS03195 WP_011680918.1 588005..590263(-) (clpE) [Streptococcus thermophilus LMD-9]
ATGCTCTGCCAAAACTGTAACCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATAAAATCTGATCCAGAGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAACTTCCGTTCTTCTAGCGGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCAGGCCGTCCTGGAGGACCACGTCAACAAGCCCCTCAACAACCTCAAGGCCT
TCTCGAAGAATATGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATCGTTGATGGAGATGTGCCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAAAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCAACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCTGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGTATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGCA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTGATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGTGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGCAACAGCAAACCATC
AAAGATCAAGATATGCCTATCATTACTGAAAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTATCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCCGCAG
TTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGACTTGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTAGGCCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACCGAAAAGGTCCGCCGTAACCCTTATTCACTCATTCTCCTTGATGAGGTTGAAAAAGCTCAC
CCAGATGTGCTTCACATGTTCCTTCAGGTACTTGATGATGGTCGTCTGACTGATGGTCAAGGGAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCAAGTGTAGGTTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTGTTATCAACCACCTCGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCTCTGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGACCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCCACCTCAGTGTGACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATCGAAGATGCCATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGATCTC
AAGGCTGTAATGACTTCAAAGGGACACATCACCATTAAATCTGCTAAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGTCAACTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(288-386)

ATPase family associated with various cellular activities (AAA) (AAA)

(150-269)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(644-717)

AAA domain (Cdc48 subfamily) (AAA_2)

(473-636)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.288

99.867

0.842
  clpE Streptococcus pneumoniae Rx1

82.181

100

0.822
  clpE Streptococcus pneumoniae D39

82.181

100

0.822
  clpE Streptococcus pneumoniae R6

82.181

100

0.822
  clpE Streptococcus pneumoniae TIGR4

82.048

100

0.82
  clpC Lactococcus lactis subsp. cremoris KW2

76.07

99.468

0.757
  clpC Bacillus subtilis subsp. subtilis str. 168

51.772

86.303

0.447
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.037

87.234

0.402
  clpC Streptococcus pneumoniae Rx1

47.143

83.777

0.395
  clpC Streptococcus pneumoniae D39

47.143

83.777

0.395
  clpC Streptococcus pneumoniae TIGR4

46.984

83.777

0.394
  clpC Streptococcus thermophilus LMD-9

46.56

83.112

0.387
  clpC Streptococcus thermophilus LMG 18311

46.24

83.112

0.384
  clpC Streptococcus mutans UA159

46.166

83.245

0.384

Multiple sequence alignment