Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | RK83_RS03135 | Genome accession | NZ_CP026069 |
| Coordinates | 598235..599863 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain FDAARGOS_25 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 593014..636739 | 598235..599863 | within | 0 |
| SCCmec | 579869..601234 | 598235..599863 | within | 0 |
Gene organization within MGE regions
Location: 579869..636739
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RK83_RS03025 (RK83_003025) | mecA | 579869..581878 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| RK83_RS03030 (RK83_003030) | mecR1 | 581975..583732 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| RK83_RS03035 (RK83_003035) | mecI | 583732..584103 (+) | 372 | WP_000369211.1 | mecA-type methicillin resistance repressor MecI | - |
| RK83_RS03040 | psm-mec | 584188..584256 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| RK83_RS03045 (RK83_003045) | - | 584611..585720 (+) | 1110 | WP_025174171.1 | ROK family transcriptional regulator | - |
| RK83_RS03055 (RK83_003055) | cstB | 585834..587168 (-) | 1335 | Protein_575 | persulfide dioxygenase-sulfurtransferase CstB | - |
| RK83_RS03060 (RK83_003060) | - | 587201..588265 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| RK83_RS03065 (RK83_003065) | cstR | 588401..588661 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| RK83_RS03070 (RK83_003070) | - | 588661..589299 (+) | 639 | Protein_578 | sulfite exporter TauE/SafE family protein | - |
| RK83_RS15315 | - | 589351..589412 (-) | 62 | Protein_579 | DNA repair protein RadC | - |
| RK83_RS03080 (RK83_003080) | - | 589644..590306 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| RK83_RS03090 (RK83_003090) | erm(A) | 590840..591571 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| RK83_RS03095 (RK83_003095) | - | 591697..592479 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| RK83_RS03100 (RK83_003100) | - | 592630..593007 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| RK83_RS03105 (RK83_003105) | - | 593014..594906 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| RK83_RS03110 (RK83_003110) | - | 594903..595988 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| RK83_RS03115 (RK83_003115) | - | 596107..596424 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| RK83_RS03120 (RK83_003120) | - | 596445..596951 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| RK83_RS03125 (RK83_003125) | - | 596969..597280 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| RK83_RS03130 (RK83_003130) | - | 597367..597717 (-) | 351 | WP_000859153.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| RK83_RS03135 (RK83_003135) | ccrB | 598235..599863 (-) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| RK83_RS03140 (RK83_003140) | ccrA | 599885..601234 (-) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| RK83_RS03145 (RK83_003145) | - | 601468..603261 (-) | 1794 | WP_000195100.1 | DUF927 domain-containing protein | - |
| RK83_RS03150 (RK83_003150) | - | 603261..603557 (-) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| RK83_RS03155 (RK83_003155) | - | 603750..604796 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| RK83_RS03160 (RK83_003160) | - | 605047..606188 (-) | 1142 | Protein_595 | IS3-like element ISSau4 family transposase | - |
| RK83_RS03165 (RK83_003165) | - | 606699..607625 (-) | 927 | Protein_596 | YfcC family protein | - |
| RK83_RS03170 (RK83_003170) | - | 608347..609042 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| RK83_RS03175 (RK83_003175) | - | 609017..611650 (-) | 2634 | WP_010922810.1 | sensor histidine kinase KdpD | - |
| RK83_RS03180 (RK83_003180) | kdpF | 611853..611933 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| RK83_RS03185 (RK83_003185) | kdpA | 611954..613630 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| RK83_RS03190 (RK83_003190) | - | 613649..615670 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| RK83_RS03195 (RK83_003195) | - | 615686..616243 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| RK83_RS03200 (RK83_003200) | - | 616788..617657 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| RK83_RS03205 (RK83_003205) | - | 617667..618563 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| RK83_RS03215 (RK83_003215) | - | 619682..620308 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| RK83_RS03220 (RK83_003220) | - | 620423..621931 (+) | 1509 | WP_001001347.1 | protein kinase | - |
| RK83_RS03225 (RK83_003225) | - | 622181..622315 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| RK83_RS03230 (RK83_003230) | - | 622279..622371 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| RK83_RS03235 (RK83_003235) | - | 622518..624263 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| RK83_RS03240 (RK83_003240) | - | 624361..624716 (-) | 356 | Protein_610 | tRNA-dihydrouridine synthase | - |
| RK83_RS03245 (RK83_003245) | - | 625021..625109 (-) | 89 | Protein_611 | hypothetical protein | - |
| RK83_RS03250 (RK83_003250) | - | 625207..625962 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| RK83_RS03255 (RK83_003255) | cstR | 625962..626222 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| RK83_RS03260 (RK83_003260) | cstA | 626359..627423 (+) | 1065 | WP_000816124.1 | persulfide response sulfurtransferase CstA | - |
| RK83_RS03265 (RK83_003265) | cstB | 627454..628788 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| RK83_RS03270 (RK83_003270) | sqr | 628807..630000 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| RK83_RS15320 | - | 630267..630481 (-) | 215 | Protein_617 | universal stress protein | - |
| RK83_RS03285 (RK83_003285) | - | 630667..631653 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| RK83_RS03290 (RK83_003290) | - | 631962..632165 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| RK83_RS03295 (RK83_003295) | - | 632214..632510 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| RK83_RS03300 (RK83_003300) | - | 632718..633320 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| RK83_RS03305 (RK83_003305) | - | 633587..636739 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=266459 RK83_RS03135 WP_001186602.1 598235..599863(-) (ccrB) [Staphylococcus aureus strain FDAARGOS_25]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=266459 RK83_RS03135 WP_001186602.1 598235..599863(-) (ccrB) [Staphylococcus aureus strain FDAARGOS_25]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |