Detailed information NTG0266450

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK82_RS10945
• Genome accession: NZ_CP026068
• Coordinates: 2093953..2094840 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_24
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2088953..2099840

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK82_RS10910 (RK82_010910)	-	2088972..2089064 (+)	93	WP_010956583.1	hypothetical protein	-
RK82_RS10915 (RK82_010915)	-	2089172..2089669 (-)	498	WP_001065268.1	glutathione peroxidase	-
RK82_RS10920 (RK82_010920)	-	2089679..2089939 (-)	261	WP_001789910.1	hypothetical protein	-
RK82_RS10930 (RK82_010930)	-	2090321..2090434 (-)	114	WP_011447078.1	hypothetical protein	-
RK82_RS10935 (RK82_010935)	-	2091093..2093093 (-)	2001	WP_000776751.1	ABC transporter permease	-
RK82_RS10940 (RK82_010940)	-	2093090..2093845 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK82_RS10945 (RK82_010945)	braS	2093953..2094840 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK82_RS10950 (RK82_010950)	braR	2094851..2095516 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK82_RS10955 (RK82_010955)	-	2095542..2095742 (-)	201	WP_000604728.1	hypothetical protein	-
RK82_RS10960 (RK82_010960)	-	2095940..2097364 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RK82_RS14095 (RK82_010965)	-	2097424..2097525 (-)	102	WP_000731972.1	SE2200 family small protein	-
RK82_RS10970 (RK82_010970)	-	2097647..2098102 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK82_RS10975 (RK82_010975)	-	2098347..2099108 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=266450 RK82_RS10945 WP_000143419.1 2093953..2094840(-) (braS) [Staphylococcus aureus strain FDAARGOS_24]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=266450 RK82_RS10945 WP_000143419.1 2093953..2094840(-) (braS) [Staphylococcus aureus strain FDAARGOS_24]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997