Detailed information NTG0266253

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK72_RS04275
• Genome accession: NZ_CP026063
• Coordinates: 763410..764297 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain FDAARGOS_14
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 758410..769297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK72_RS04240 (RK72_004240)	-	758429..758521 (+)	93	WP_010956583.1	hypothetical protein	-
RK72_RS04245 (RK72_004245)	-	758629..759126 (-)	498	WP_001065268.1	glutathione peroxidase	-
RK72_RS04250 (RK72_004250)	-	759136..759396 (-)	261	WP_001791974.1	hypothetical protein	-
RK72_RS04260 (RK72_004260)	-	759778..759891 (-)	114	Protein_784	hypothetical protein	-
RK72_RS04265 (RK72_004265)	-	760550..762550 (-)	2001	WP_000776751.1	ABC transporter permease	-
RK72_RS04270 (RK72_004270)	-	762547..763302 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK72_RS04275 (RK72_004275)	braS	763410..764297 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK72_RS04280 (RK72_004280)	braR	764308..764973 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK72_RS04285 (RK72_004285)	-	764999..765199 (-)	201	WP_000604730.1	hypothetical protein	-
RK72_RS04290 (RK72_004290)	-	765397..766821 (+)	1425	WP_000953755.1	alkaline phosphatase	-
RK72_RS14620 (RK72_004295)	-	766881..766982 (-)	102	WP_000731976.1	SE2200 family small protein	-
RK72_RS04300 (RK72_004300)	-	767104..767559 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK72_RS04305 (RK72_004305)	-	767804..768565 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=266253 RK72_RS04275 WP_000143425.1 763410..764297(-) (braS) [Staphylococcus aureus strain FDAARGOS_14]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=266253 RK72_RS04275 WP_000143425.1 763410..764297(-) (braS) [Staphylococcus aureus strain FDAARGOS_14]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1