Detailed information NTG0266248

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RK72_RS00210
• Genome accession: NZ_CP026063
• Coordinates: 29547..30590 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_14
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 24547..35590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK72_RS00180 (RK72_000180)	-	24968..26224 (-)	1257	WP_001795108.1	aminopeptidase	-
RK72_RS00185 (RK72_000185)	-	26227..26427 (-)	201	WP_000180460.1	DUF1128 family protein	-
RK72_RS00190 (RK72_000190)	-	26574..27038 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RK72_RS00195 (RK72_000195)	-	27045..27320 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RK72_RS00200 (RK72_000200)	-	27598..28815 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RK72_RS00205 (RK72_000205)	vraR	28928..29557 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RK72_RS00210 (RK72_000210)	vraS	29547..30590 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RK72_RS00215 (RK72_000215)	liaF	30587..31288 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RK72_RS00220 (RK72_000220)	-	31303..31689 (-)	387	WP_001110179.1	hypothetical protein	-
RK72_RS00225 (RK72_000225)	map	31906..32664 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RK72_RS00235 (RK72_000235)	-	33195..34181 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
RK72_RS00245 (RK72_000245)	-	34612..35025 (-)	414	WP_001557448.1	hypothetical protein	-
RK72_RS00250 (RK72_000250)	-	35054..35164 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=266248 RK72_RS00210 WP_001017131.1 29547..30590(-) (vraS) [Staphylococcus aureus strain FDAARGOS_14]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=266248 RK72_RS00210 WP_001017131.1 29547..30590(-) (vraS) [Staphylococcus aureus strain FDAARGOS_14]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1