Detailed information NTG0266196

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DV947_RS07515
• Genome accession: NZ_CP031545
• Coordinates: 1421850..1423949 (-)
• Length: 699 a.a.
• NCBI ID: WP_116920338.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST109
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1416850..1428949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV947_RS07485 (DV947_07490)	pptB	1417316..1418353 (-)	1038	WP_014621893.1	ABC transporter permease	Regulator
DV947_RS07490 (DV947_07495)	pptA	1418350..1419081 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
DV947_RS07495 (DV947_07500)	-	1419146..1419565 (+)	420	WP_011227486.1	HIT family protein	-
DV947_RS07500 (DV947_07505)	-	1419562..1419870 (+)	309	WP_116920336.1	hypothetical protein	-
DV947_RS07505 (DV947_07510)	-	1419912..1420643 (-)	732	WP_116920337.1	hypothetical protein	-
DV947_RS07510 (DV947_07515)	-	1420661..1421296 (-)	636	WP_023909894.1	DUF4230 domain-containing protein	-
DV947_RS10475	-	1421315..1421440 (-)	126	WP_259699999.1	hypothetical protein	-
DV947_RS07515 (DV947_07520)	clpE	1421850..1423949 (-)	2100	WP_116920338.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DV947_RS07520 (DV947_07525)	-	1424664..1425755 (-)	1092	WP_011681536.1	nucleotidyltransferase	-
DV947_RS07525 (DV947_07530)	-	1425762..1426502 (-)	741	WP_277426406.1	class I SAM-dependent methyltransferase	-
DV947_RS07535 (DV947_07540)	rsfS	1426827..1427180 (-)	354	WP_011227491.1	ribosome silencing factor	-
DV947_RS07540 (DV947_07545)	yqeK	1427204..1427794 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
DV947_RS07545 (DV947_07550)	-	1427791..1428423 (-)	633	WP_002951698.1	nicotinate-nucleotide adenylyltransferase	-
DV947_RS07550 (DV947_07555)	yhbY	1428527..1428844 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77198.07 Da
• Isoelectric Point: 4.8262

>NTDB_id=266196 DV947_RS07515 WP_116920338.1 1421850..1423949(-) (clpE) [Streptococcus thermophilus strain ST109]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATDIE
RLKDMSNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=266196 DV947_RS07515 WP_116920338.1 1421850..1423949(-) (clpE) [Streptococcus thermophilus strain ST109]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGAGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• AAA lid domain (AAA_lid_9) (255-349)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.781	100	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	49.062	91.559	0.449
clpE	Streptococcus pneumoniae TIGR4	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	46.285	92.418	0.428
clpC	Streptococcus thermophilus LMD-9	43.417	91.273	0.396
clpC	Streptococcus thermophilus LMG 18311	43.26	91.273	0.395
clpC	Streptococcus pneumoniae Rx1	43.499	89.127	0.388
clpC	Streptococcus pneumoniae D39	43.499	89.127	0.388
clpC	Streptococcus pneumoniae TIGR4	43.499	89.127	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.436	88.269	0.383
clpC	Streptococcus mutans UA159	43.156	88.841	0.383