Detailed information NTG0266128

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DV947_RS00315
• Genome accession: NZ_CP031545
• Coordinates: 54259..56817 (+)
• Length: 852 a.a.
• NCBI ID: WP_014607836.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST109
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 49259..61817

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV947_RS00295 (DV947_00295)	purB	49472..50770 (+)	1299	WP_116920082.1	adenylosuccinate lyase	-
DV947_RS00300 (DV947_00300)	argS	51633..53324 (-)	1692	WP_116920083.1	arginine--tRNA ligase	-
DV947_RS00305 (DV947_00305)	argR	53479..53907 (+)	429	WP_024704313.1	arginine repressor	-
DV947_RS00310 (DV947_00310)	-	53907..54266 (+)	360	WP_011225277.1	YlbF family regulator	-
DV947_RS00315 (DV947_00315)	hexA	54259..56817 (+)	2559	WP_014607836.1	DNA mismatch repair protein MutS	Machinery gene
DV947_RS10490 (DV947_00320)	-	56851..57306 (-)	456	Protein_42	DUF3021 domain-containing protein	-
DV947_RS00325 (DV947_00325)	-	57303..57694 (-)	392	Protein_43	LytTR family DNA-binding domain-containing protein	-
DV947_RS00330 (DV947_00330)	-	57918..58223 (+)	306	WP_002949050.1	hypothetical protein	-
DV947_RS00335 (DV947_00335)	hexB	58275..60218 (+)	1944	WP_011225282.1	DNA mismatch repair endonuclease MutL	Machinery gene
DV947_RS00340 (DV947_00340)	-	60348..60569 (+)	222	WP_002949052.1	hypothetical protein	-
DV947_RS00345 (DV947_00345)	ruvA	60721..61311 (+)	591	WP_011680603.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95483.73 Da
• Isoelectric Point: 4.7412

>NTDB_id=266128 DV947_RS00315 WP_014607836.1 54259..56817(+) (hexA) [Streptococcus thermophilus strain ST109]
MAKEKISPGMQQYLDIKKNYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSANNFLVAIDKVGSRFGLSYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLLETDEQVLVNQLNLLLSKETEGYDDVHLIGNSLTDLESSVASKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDKTKTAMGMRLLRTWIDRPLVNQASIIERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDDTLSGLLQELDALPELESLIRSAIDP
DAPATITEGGIIRDGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIAIDRGRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSVDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNSLIHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPTDLLNRADTILTQLEGETVVIQPQEKVSSQ
EKPAIETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=266128 DV947_RS00315 WP_014607836.1 54259..56817(+) (hexA) [Streptococcus thermophilus strain ST109]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGAAAAATTATCCAGATGCTTTTTTGCTGTT
TCGGATGGGGGATTTTTACGAATTATTTTACGATGATGCTGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACTAGCC
GTAATAAGAATGCAGATAATCCCATTCCTATGGCAGGTGTGCCTTATCATTCAGCTCAAGCATACATTGATGTTTTGGTT
GAGATGGGCTACAAGGTAGCCATTGCTGAGCAGATGGAGGATCCTAAGCAGGCTGTCGGTGTGGTAAAGCGTGAGGTTGT
TCAGGTTATCACACCAGGTACAGTGGTTGACAGCTCTAAACCTGATAGTGCCAACAATTTCTTGGTGGCCATTGACAAGG
TTGGAAGTCGTTTTGGTCTTTCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGATGATTTTAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTGGTTGGATATGATCTACTTGAAACTGACGAACAAGTTTT
AGTGAACCAACTTAACCTACTTCTCTCCAAGGAAACAGAAGGTTACGATGATGTTCACTTGATTGGTAATAGCTTGACAG
ATTTGGAAAGCAGTGTGGCAAGTAAACTTCTCCAGTATGTTCATCGCACTCAGATGCGTGAGCTCAGTCATTTACAAAAA
GCTCAGCACTATGAGATAAAGGATTACTTGCAGATGTCCTATGCGACCAAGTCAAGCTTGGATTTACTGGAAAATGCTAG
AACGGGCAAGAAACACGGTTCTCTTTTCTGGCTCTTGGATAAAACCAAGACAGCCATGGGAATGCGTCTCTTGCGAACTT
GGATTGATCGTCCTTTAGTGAATCAAGCCAGCATCATAGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTT
GAGCGTAGTGACTTGACCGAGAGTCTAAAAGGTGTTTACGATATTGAGCGTCTGGCCAGTCGTGTTTCCTTTGGCAAGGC
TAATCCTAAAGATTTAATTCAGCTAGGTCATACCTTAGCTCAGGTTCCGGTCATTAAGGCAATCTTGGAGTCCTTTAATG
ACGATACCTTGTCAGGTCTTTTACAAGAGTTAGATGCTTTGCCAGAATTAGAGAGTTTGATTCGTTCGGCTATTGATCCT
GATGCTCCAGCAACAATTACAGAAGGTGGTATTATTCGTGATGGTTTTGATGAGACCTTGGACAAGTATCGCAAAGTGAT
GAGCGAGGGGACGTCATGGATTGCGGATATCGAAGCAAAAGAACGCGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAACCTTAGTTTGGTTCCTGACCATTTCTTCCGTAAGGCG
ACACTGAAAAATTCGGAGCGTTTTGGAACTGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTAGAAGCACGTGAAAAATC
GTCAACCCTAGAGTATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATCGACCGTTTGCAGTCTTTGGCTA
AGGCCATTGCAACAGTCGATGTGCTTCAGAGTTTGGCTGTTACAGCGGAGACAAATCATTATGTTCGTCCTGTTTTTAAT
GATGAGCATCGTATCGCTATTGATCGGGGCCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAA
TACGATTACCTTTGACAGTCAGACCAATATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACCTATATGCGGC
AGTTAGCCTTGTCAGTAGTTATGGCTCAAATGGGGGCTTACGTACCAGCAGATAGTGTTGATTTACCTGTTTTTGACGCC
ATCTATACACGTATAGGTGCCGCAGATGACCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCA
GGCCATTAAGCGAGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGGCGTGGGACAGCCACTTATGATGGTATGG
CTTTGGCCCAGTCTATTATTGAGTTTATTCATGACAAGGTTGGGGCTAAGACCATGTTTGCTACCCATTATCATGAGTTG
ACTGCGCTGTCAAACAGTTTGATACACCTTGTCAACGTCCATGTTGCGACACTTGAAAAGGATGGCGAAGTGACTTTCCT
CCACAAAATTGTCGATGGTCCAGCCGATAAATCGTATGGTATTCATGTAGCTAAAATTGCAGGTTTACCAACAGATTTAT
TGAACCGTGCTGACACCATATTGACACAATTAGAAGGAGAGACAGTTGTAATCCAACCTCAGGAAAAGGTATCGTCTCAA
GAAAAGCCTGCCATTGAAACGCATGTCAACGAGCAAATCTCTCTCTTTGATGACTTTACTGAAAATCCGGTTCTTCAAGA
GTTGCGTGATTTGGACATTTACAACATGACACCGATGCAAGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.061	100	0.741
mutS	Pseudomonas stutzeri strain ATCC 17587	35.788	100	0.365