Detailed information
Bioinformatically predicted
Overview
| Name | nucA/comI | Type | Machinery gene |
| Locus tag | C2H94_RS02270 | Genome accession | NZ_CP026034 |
| Coordinates | 385871..386281 (-) | Length | 136 a.a. |
| NCBI ID | WP_009967785.1 | Uniprot ID | A0A6I4D881 |
| Organism | Bacillus subtilis strain PK5_52 | ||
| Function | cleavage of dsDNA into ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 386849..417345 | 385871..386281 | flank | 568 |
Gene organization within MGE regions
Location: 385871..417345
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C2H94_RS02270 (C2H94_02255) | nucA/comI | 385871..386281 (-) | 411 | WP_009967785.1 | sporulation-specific Dnase NucB | Machinery gene |
| C2H94_RS02275 (C2H94_02260) | - | 386477..386827 (+) | 351 | Protein_452 | sigma-70 family RNA polymerase sigma factor | - |
| C2H94_RS02280 (C2H94_02265) | - | 386849..387268 (-) | 420 | WP_249849480.1 | NUDIX domain-containing protein | - |
| C2H94_RS02285 (C2H94_02270) | spoIVCA | 387336..388796 (-) | 1461 | WP_249849668.1 | site-specific DNA recombinase SpoIVCA | - |
| C2H94_RS02290 (C2H94_02275) | - | 388754..388932 (-) | 179 | Protein_455 | hypothetical protein | - |
| C2H94_RS02295 (C2H94_02280) | - | 389178..390992 (-) | 1815 | WP_249849481.1 | AAA family ATPase | - |
| C2H94_RS02300 (C2H94_02285) | - | 391994..396304 (-) | 4311 | WP_249849482.1 | ATP-binding protein | - |
| C2H94_RS02305 (C2H94_02290) | rapE | 396575..397702 (+) | 1128 | WP_249849483.1 | response regulator aspartate phosphatase RapE | - |
| C2H94_RS02310 (C2H94_02295) | phrE | 397692..397826 (+) | 135 | WP_014114495.1 | phosphatase RapE inhibitor PhrE | - |
| C2H94_RS02315 (C2H94_02300) | - | 397936..398095 (+) | 160 | Protein_460 | hypothetical protein | - |
| C2H94_RS21080 (C2H94_02305) | - | 398464..400422 (+) | 1959 | WP_283939287.1 | T7SS effector LXG polymorphic toxin | - |
| C2H94_RS02330 (C2H94_02310) | - | 400441..400983 (+) | 543 | WP_043857857.1 | T6SS immunity protein Tdi1 domain-containing protein | - |
| C2H94_RS02335 (C2H94_02315) | - | 401317..401592 (-) | 276 | WP_249849484.1 | barstar family protein | - |
| C2H94_RS02340 (C2H94_02320) | - | 401887..402738 (+) | 852 | WP_249853176.1 | hypothetical protein | - |
| C2H94_RS02345 (C2H94_02325) | - | 402755..403132 (+) | 378 | WP_032725168.1 | DUF3139 domain-containing protein | - |
| C2H94_RS02350 (C2H94_02330) | cwlA | 403159..403977 (-) | 819 | WP_249849485.1 | N-acetylmuramoyl-L-alanine amidase | - |
| C2H94_RS02355 (C2H94_02335) | - | 404022..404162 (-) | 141 | Protein_467 | phage holin family protein | - |
| C2H94_RS02360 (C2H94_02340) | - | 404189..404374 (-) | 186 | Protein_468 | phage terminase large subunit | - |
| C2H94_RS02365 (C2H94_02345) | terS | 404371..405096 (-) | 726 | WP_249849486.1 | phage terminase small subunit | - |
| C2H94_RS02370 (C2H94_02350) | - | 405439..405876 (-) | 438 | WP_119996313.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| C2H94_RS02375 (C2H94_02355) | - | 406097..406957 (-) | 861 | WP_119996311.1 | hypothetical protein | - |
| C2H94_RS02380 (C2H94_02360) | - | 407313..407579 (+) | 267 | WP_249849487.1 | transcriptional regulator | - |
| C2H94_RS02385 (C2H94_02365) | yqaO | 407718..407924 (-) | 207 | WP_024122227.1 | XtrA/YqaO family protein | - |
| C2H94_RS02390 (C2H94_02370) | yqaN | 408006..408434 (-) | 429 | WP_249849488.1 | RusA family crossover junction endodeoxyribonuclease | - |
| C2H94_RS02395 (C2H94_02375) | - | 408530..408679 (-) | 150 | WP_003229910.1 | hypothetical protein | - |
| C2H94_RS02400 (C2H94_02380) | sknM | 408670..409611 (-) | 942 | WP_249849489.1 | ATP-binding protein | - |
| C2H94_RS02405 (C2H94_02385) | yqaL | 409493..410167 (-) | 675 | WP_249849669.1 | DnaD domain protein | - |
| C2H94_RS02410 (C2H94_02390) | yqaK | 410244..411098 (-) | 855 | WP_249849490.1 | recombinase RecT | - |
| C2H94_RS02415 (C2H94_02395) | yqaJ | 411101..412060 (-) | 960 | WP_249849491.1 | YqaJ viral recombinase family protein | - |
| C2H94_RS02420 (C2H94_02400) | - | 412166..412360 (-) | 195 | WP_249849492.1 | hypothetical protein | - |
| C2H94_RS02425 | - | 412320..412493 (-) | 174 | WP_125825444.1 | hypothetical protein | - |
| C2H94_RS02430 (C2H94_02405) | sknH | 412490..412747 (-) | 258 | WP_032722183.1 | YqaH family protein | - |
| C2H94_RS02435 (C2H94_02410) | yqaG | 412744..413313 (-) | 570 | WP_015714341.1 | helix-turn-helix transcriptional regulator | - |
| C2H94_RS02440 (C2H94_02415) | - | 413385..413525 (-) | 141 | WP_032679254.1 | hypothetical protein | - |
| C2H94_RS02445 (C2H94_02420) | yqaF | 413555..413785 (-) | 231 | WP_080332276.1 | helix-turn-helix transcriptional regulator | - |
| C2H94_RS02450 (C2H94_02425) | sknR | 413962..414312 (+) | 351 | WP_004398704.1 | transcriptional regulator SknR | - |
| C2H94_RS02455 (C2H94_02430) | - | 414553..414909 (+) | 357 | WP_249849493.1 | hypothetical protein | - |
| C2H94_RS02460 (C2H94_02435) | aadK | 415003..415857 (-) | 855 | WP_249849494.1 | aminoglycoside 6-adenylyltransferase AadK | - |
| C2H94_RS02465 (C2H94_02440) | yqaB | 416108..416626 (+) | 519 | WP_249849495.1 | ImmA/IrrE family metallo-endopeptidase | - |
| C2H94_RS02470 (C2H94_02445) | - | 416632..417024 (+) | 393 | Protein_490 | sigma-70 family RNA polymerase sigma factor | - |
| C2H94_RS02475 | - | 417024..417140 (+) | 117 | WP_042976632.1 | hypothetical protein | - |
| C2H94_RS02480 (C2H94_02450) | - | 417106..417303 (-) | 198 | Protein_492 | recombinase family protein | - |
Sequence
Protein
Download Length: 136 a.a. Molecular weight: 14967.97 Da Isoelectric Point: 5.1853
>NTDB_id=265441 C2H94_RS02270 WP_009967785.1 385871..386281(-) (nucA/comI) [Bacillus subtilis strain PK5_52]
MKKWMAGLFLAAAVLLCLMVPQQIQGASSYDKVLYFPLSRYPETGSHIRDAIAEGHPDICTIDRDGADKRREESLKGIPT
KPGYDRDEWPMAVCEEGGAGADVRYVTPSDNRGAGSWVGNQMSSYPDGTRVLFIVQ
MKKWMAGLFLAAAVLLCLMVPQQIQGASSYDKVLYFPLSRYPETGSHIRDAIAEGHPDICTIDRDGADKRREESLKGIPT
KPGYDRDEWPMAVCEEGGAGADVRYVTPSDNRGAGSWVGNQMSSYPDGTRVLFIVQ
Nucleotide
Download Length: 411 bp
>NTDB_id=265441 C2H94_RS02270 WP_009967785.1 385871..386281(-) (nucA/comI) [Bacillus subtilis strain PK5_52]
ATGAAAAAATGGATGGCAGGCCTGTTTCTTGCTGCAGCAGTTCTTCTTTGTTTAATGGTTCCGCAGCAGATCCAAGGCGC
ATCTTCGTATGACAAAGTGTTATATTTTCCGCTGTCTCGTTATCCGGAAACCGGTAGTCATATTAGAGATGCGATTGCAG
AGGGACATCCAGATATTTGTACCATTGACAGAGATGGAGCAGACAAAAGGCGGGAGGAATCTTTAAAGGGAATCCCGACC
AAGCCGGGCTATGACCGGGATGAGTGGCCGATGGCGGTCTGCGAGGAAGGCGGCGCAGGGGCTGATGTCCGATATGTGAC
GCCTTCTGATAATCGCGGCGCCGGCTCGTGGGTAGGGAATCAAATGAGCAGCTATCCTGACGGTACCAGAGTGCTGTTTA
TTGTGCAGTAG
ATGAAAAAATGGATGGCAGGCCTGTTTCTTGCTGCAGCAGTTCTTCTTTGTTTAATGGTTCCGCAGCAGATCCAAGGCGC
ATCTTCGTATGACAAAGTGTTATATTTTCCGCTGTCTCGTTATCCGGAAACCGGTAGTCATATTAGAGATGCGATTGCAG
AGGGACATCCAGATATTTGTACCATTGACAGAGATGGAGCAGACAAAAGGCGGGAGGAATCTTTAAAGGGAATCCCGACC
AAGCCGGGCTATGACCGGGATGAGTGGCCGATGGCGGTCTGCGAGGAAGGCGGCGCAGGGGCTGATGTCCGATATGTGAC
GCCTTCTGATAATCGCGGCGCCGGCTCGTGGGTAGGGAATCAAATGAGCAGCTATCCTGACGGTACCAGAGTGCTGTTTA
TTGTGCAGTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| nucA/comI | Bacillus subtilis subsp. subtilis str. 168 |
62.609 |
84.559 |
0.529 |