Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DXE50_RS13260 Genome accession   NZ_CP031353
Coordinates   2326888..2327544 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O145 strain RM9154-C1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2321888..2332544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE50_RS13230 (DXE50_13750) dcyD 2322767..2323753 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  DXE50_RS13235 (DXE50_13755) tcyL 2323768..2324436 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  DXE50_RS13240 (DXE50_13760) tcyN 2324433..2325185 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  DXE50_RS13245 (DXE50_13765) sdiA 2325415..2326137 (+) 723 WP_001154283.1 transcriptional regulator SdiA -
  DXE50_RS13250 (DXE50_13770) yecF 2326205..2326429 (-) 225 WP_000106476.1 DUF2594 family protein YecF -
  DXE50_RS13255 (DXE50_13775) yecU 2326416..2326592 (-) 177 WP_001307856.1 protein YecU -
  DXE50_RS13260 (DXE50_13780) letA 2326888..2327544 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  DXE50_RS13265 (DXE50_13785) uvrC 2327541..2329373 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  DXE50_RS13270 (DXE50_13790) pgsA 2329430..2329978 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  DXE50_RS27590 (DXE50_13810) - 2330674..2330934 (-) 261 Protein_2227 hypothetical protein -
  DXE50_RS13290 (DXE50_13815) - 2330978..2332192 (-) 1215 Protein_2228 IS3 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=265271 DXE50_RS13260 WP_000611328.1 2326888..2327544(+) (letA) [Escherichia coli O145 strain RM9154-C1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=265271 DXE50_RS13260 WP_000611328.1 2326888..2327544(+) (letA) [Escherichia coli O145 strain RM9154-C1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment