Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SPYM_RS05215 Genome accession   NC_009332
Coordinates   1029418..1029894 (-) Length   158 a.a.
NCBI ID   WP_011017701.1    Uniprot ID   -
Organism   Streptococcus pyogenes str. Manfredo     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1024418..1034894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS05200 (SpyM51017) fbp54 1025231..1026883 (+) 1653 WP_011888922.1 Rqc2 family fibronectin-binding protein Fbp54 -
  SPYM_RS05205 (SpyM51018) - 1026942..1028189 (-) 1248 WP_002984878.1 tetratricopeptide repeat protein -
  SPYM_RS05210 (SpyM51019) - 1028179..1029360 (-) 1182 WP_002990002.1 AI-2E family transporter -
  SPYM_RS05215 (SpyM51020) mutX 1029418..1029894 (-) 477 WP_011017701.1 NUDIX hydrolase Machinery gene
  SPYM_RS05220 (SpyM51021) speh 1030498..1031208 (-) 711 WP_010922229.1 streptococcal pyrogenic exotoxin SpeH -
  SPYM_RS05225 (SpyM51024) spei 1031234..1031910 (-) 677 Protein_983 streptococcal pyrogenic exotoxin SpeI -
  SPYM_RS05230 (SpyM51025) - 1032184..1033518 (-) 1335 WP_011888923.1 GH25 family lysozyme -
  SPYM_RS05240 (SpyM51026) - 1033630..1033815 (-) 186 WP_002990010.1 holin -
  SPYM_RS05245 (SpyM51027) - 1033812..1034108 (-) 297 WP_002990012.1 hypothetical protein -
  SPYM_RS05250 (SpyM51028) - 1034118..1034750 (-) 633 WP_011888924.1 hypothetical protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18474.74 Da        Isoelectric Point: 4.3268

>NTDB_id=26491 SPYM_RS05215 WP_011017701.1 1029418..1029894(-) (mutX) [Streptococcus pyogenes str. Manfredo]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVIEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=26491 SPYM_RS05215 WP_011017701.1 1029418..1029894(-) (mutX) [Streptococcus pyogenes str. Manfredo]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTATAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment