Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DV130_RS11585 Genome accession   NZ_CP031248
Coordinates   2126180..2126857 (+) Length   225 a.a.
NCBI ID   WP_000548964.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26365     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2121180..2131857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS11550 - 2121547..2122254 (-) 708 WP_000749120.1 nicotinamide mononucleotide transporter family protein -
  DV130_RS11560 - 2122373..2123023 (-) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  DV130_RS11565 - 2123135..2123977 (+) 843 WP_000160934.1 metallophosphoesterase family protein -
  DV130_RS11570 - 2124053..2124490 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  DV130_RS11575 - 2124558..2124860 (+) 303 WP_000281608.1 hypothetical protein -
  DV130_RS11580 - 2124951..2126024 (-) 1074 WP_001273814.1 DUF2974 domain-containing protein -
  DV130_RS11585 braR 2126180..2126857 (+) 678 WP_000548964.1 response regulator transcription factor Regulator
  DV130_RS11590 - 2126850..2127824 (+) 975 WP_050072233.1 HAMP domain-containing histidine kinase -
  DV130_RS11595 thrS 2127873..2129816 (-) 1944 WP_000608353.1 threonine--tRNA ligase -
  DV130_RS11600 - 2129874..2130050 (-) 177 WP_000166031.1 MazG-like protein -
  DV130_RS11605 - 2130057..2130197 (-) 141 WP_000422775.1 MazG-like protein -
  DV130_RS11620 - 2130628..2130828 (-) 201 WP_001826938.1 hypothetical protein -
  DV130_RS11625 - 2131067..2131696 (+) 630 Protein_2166 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25949.19 Da        Isoelectric Point: 5.6311

>NTDB_id=263441 DV130_RS11585 WP_000548964.1 2126180..2126857(+) (braR) [Streptococcus pneumoniae strain M26365]
MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMKVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=263441 DV130_RS11585 WP_000548964.1 2126180..2126857(+) (braR) [Streptococcus pneumoniae strain M26365]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGAAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCAGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAACGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGATCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471

Multiple sequence alignment