Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SSA_RS08200 Genome accession   NC_009009
Coordinates   1678480..1679166 (-) Length   228 a.a.
NCBI ID   WP_011837285.1    Uniprot ID   A3CPG4
Organism   Streptococcus sanguinis SK36     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1673480..1684166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS08180 (SSA_1681) - 1675271..1676050 (-) 780 WP_002899832.1 ABC transporter ATP-binding protein -
  SSA_RS08185 (SSA_1682) - 1676220..1676975 (-) 756 WP_011837282.1 TraX family protein -
  SSA_RS08190 (SSA_1683) - 1677124..1677504 (-) 381 WP_033179196.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  SSA_RS08195 (SSA_1684) - 1677516..1678496 (-) 981 WP_011837284.1 sensor histidine kinase -
  SSA_RS08200 (SSA_1685) braR 1678480..1679166 (-) 687 WP_011837285.1 response regulator transcription factor Regulator
  SSA_RS08205 (SSA_1686) - 1679316..1680530 (+) 1215 WP_011837286.1 DUF2974 domain-containing protein -
  SSA_RS08210 (SSA_1687) - 1680687..1681883 (+) 1197 WP_011837287.1 ferredoxin reductase family protein -
  SSA_RS08215 (SSA_1689) - 1682035..1682595 (-) 561 WP_011837288.1 hypothetical protein -
  SSA_RS08220 (SSA_1690) - 1682881..1683408 (+) 528 WP_002897096.1 DUF2975 domain-containing protein -
  SSA_RS08225 (SSA_1691) - 1683421..1683630 (+) 210 WP_002894739.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26275.45 Da        Isoelectric Point: 5.3362

>NTDB_id=26313 SSA_RS08200 WP_011837285.1 1678480..1679166(-) (braR) [Streptococcus sanguinis SK36]
MHKILLVEDDPVIRQMIKKMLEQWGFQVVAVEDFMDVLTIFVREDPHLVLMDIGLPLFNGYHWCQEIRKISTVPIMFLSS
RDQSMDIVMAINMGADDYVTKPFDNNVFLAKVQGLLRRSYEFGNDQSLLEHQGVILNLKSTDLVFEGKVVTLTKNEFQIL
RVLFEHSDGIVARDDLMKELWNSDFFIDDNTLSVNVARLRKKLEEHGLKNFIETKKGIGYGLINGHTG

Nucleotide


Download         Length: 687 bp        

>NTDB_id=26313 SSA_RS08200 WP_011837285.1 1678480..1679166(-) (braR) [Streptococcus sanguinis SK36]
ATGCATAAGATTTTACTAGTAGAAGATGATCCAGTCATCCGCCAAATGATAAAAAAAATGCTAGAACAATGGGGCTTTCA
GGTGGTAGCAGTCGAAGACTTTATGGATGTGCTGACTATCTTTGTCCGAGAGGACCCGCATCTGGTGCTGATGGATATTG
GCCTGCCCTTATTTAATGGTTATCACTGGTGCCAGGAAATCCGCAAGATTTCAACAGTGCCCATCATGTTTTTGTCTTCC
CGCGATCAGTCCATGGACATTGTTATGGCTATCAATATGGGGGCAGATGACTATGTGACCAAGCCTTTTGACAATAATGT
CTTTCTGGCTAAAGTTCAGGGCTTGCTGCGCCGTTCCTATGAGTTTGGAAACGACCAGAGTCTCCTGGAGCACCAGGGTG
TCATTCTCAATCTCAAGTCGACAGATCTGGTCTTTGAGGGGAAAGTGGTGACTTTGACCAAGAACGAATTTCAGATTTTG
CGGGTCCTCTTCGAGCACTCGGATGGTATCGTAGCGCGTGATGACCTGATGAAGGAACTCTGGAACAGTGACTTTTTCAT
CGACGACAATACCCTATCGGTCAATGTCGCTCGCCTGCGTAAGAAGCTTGAAGAGCACGGACTTAAAAACTTCATCGAAA
CCAAAAAAGGAATAGGATACGGTCTCATCAATGGACACACAGGATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3CPG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

95.614

0.465

Multiple sequence alignment