Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   C6669_RS09360 Genome accession   NZ_CP031134
Coordinates   1784843..1785433 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain CFSAN064035     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1779843..1790433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6669_RS09315 (C6669_09315) emrD 1780326..1781510 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  C6669_RS29515 ysdE 1781592..1781666 (+) 75 WP_211180519.1 protein YsdE -
  C6669_RS09325 (C6669_09325) tisB 1781929..1782018 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  C6669_RS09345 (C6669_09345) ivbL 1782582..1782680 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  C6669_RS09350 (C6669_09350) ilvB 1782786..1784474 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  C6669_RS09355 (C6669_09355) ilvN 1784478..1784768 (+) 291 WP_001181713.1 acetolactate synthase small subunit -
  C6669_RS09360 (C6669_09360) letA 1784843..1785433 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  C6669_RS09365 (C6669_09365) uhpB 1785433..1786935 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  C6669_RS09370 (C6669_09370) uhpC 1786945..1788264 (+) 1320 WP_024198525.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  C6669_RS09375 (C6669_09375) uhpT 1788402..1789793 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=262363 C6669_RS09360 WP_000633668.1 1784843..1785433(+) (letA) [Escherichia coli strain CFSAN064035]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=262363 C6669_RS09360 WP_000633668.1 1784843..1785433(+) (letA) [Escherichia coli strain CFSAN064035]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment