Detailed information NTG0262331

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: C0J00_RS01005
• Genome accession: NZ_CP025536
• Coordinates: 183081..185519 (+)
• Length: 812 a.a.
• NCBI ID: WP_104967143.1
• Uniprot ID: A0A2L0D2K7
• Organism: Streptococcus pluranimalium strain TH11417
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 178081..190519

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C0J00_RS00990 (C0J00_00990)	rpsB	180392..181153 (+)	762	WP_104967140.1	30S ribosomal protein S2	-
C0J00_RS00995 (C0J00_00995)	tsf	181385..182425 (+)	1041	WP_104967141.1	translation elongation factor Ts	-
C0J00_RS01000 (C0J00_01000)	-	182620..183081 (+)	462	WP_104967142.1	CtsR family transcriptional regulator	-
C0J00_RS01005 (C0J00_01005)	clpC	183081..185519 (+)	2439	WP_104967143.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
C0J00_RS01010 (C0J00_01010)	-	185743..186414 (+)	672	WP_104967144.1	response regulator transcription factor	-
C0J00_RS01015 (C0J00_01015)	-	186416..187777 (+)	1362	WP_104967145.1	sensor histidine kinase	-
C0J00_RS01020 (C0J00_01020)	-	187951..188667 (+)	717	WP_104967146.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
C0J00_RS01025 (C0J00_01025)	-	188741..189499 (+)	759	WP_158667295.1	PrsW family glutamic-type intramembrane protease	-

Sequence

Protein

• Length: 812 a.a.
• Molecular weight: 90163.36 Da
• Isoelectric Point: 5.4949

>NTDB_id=262331 C0J00_RS01005 WP_104967143.1 183081..185519(+) (clpC) [Streptococcus pluranimalium strain TH11417]
MVKYSQKMQDVFGLSQIIATRFSCQLLESWHLLLGLISSDETIAGLTFREFDSETGENDYFAAAILASEKTFDDSINHFD
FHEQSVATADMLAFAEQISLITGDDEVGTEHVLMAMLLSPDRMPIRVLELAGFKLKNDGEGASIFSIRQGLEKHAGFTKD
QVKAIHELKKPKRPKANNFTDMMKPPSTAGELSDFTRDLTAMAEAGALEAVVGRDKEVSRMVQVLSRKTKNNPVLVGDAG
VGKTALAYGLAQRIASGEIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGHIILFVDEMHTIMGSGSGI
DSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKIVIEEPSVADAFEILKGLRPSYEAYHHVSLSDEA
LMTAVKSAHRYMTSKNLPDSAIDLMDEASATVQTMVKKEAQVELSPIDEALLDGDFKAVSRLLKKEEKVALPKVIKVTEE
HIMSTLSRLTGIPVEKMTQADNQKYLNLEKELHKRVIGQDTAISAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTEL
AKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRQKPYSVLLFDEVEKAHPDIFNVLLQVL
DDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVQDLSHDHDAMEKRILEELKKAYRPEFINRIDEKVVFHSL
TQDHMREVVKIMVQPLIKQLAEKGIVLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLAELVLSGQLATGNTLKI
GVKQGKLKFDVV

Nucleotide

• Length: 2439 bp

>NTDB_id=262331 C0J00_RS01005 WP_104967143.1 183081..185519(+) (clpC) [Streptococcus pluranimalium strain TH11417]
ATGGTTAAGTATTCACAAAAAATGCAGGATGTTTTTGGCCTGTCTCAAATTATTGCTACACGATTTTCTTGTCAGCTCTT
AGAAAGTTGGCATCTTTTACTTGGATTGATTTCTAGTGATGAAACAATTGCAGGGCTGACTTTCCGAGAATTCGATAGCG
AAACTGGTGAGAATGATTATTTTGCAGCAGCTATTTTAGCGTCAGAAAAGACTTTTGATGATAGTATCAATCACTTTGAT
TTTCATGAACAATCAGTTGCAACGGCTGATATGTTGGCTTTTGCGGAGCAAATTAGTCTTATTACTGGAGATGATGAAGT
CGGTACGGAGCATGTTCTCATGGCTATGCTTTTAAGTCCTGACAGGATGCCTATCCGTGTCCTTGAGTTAGCTGGTTTCA
AACTAAAAAATGATGGCGAAGGCGCTTCAATTTTTAGTATTCGCCAAGGTTTAGAGAAGCATGCTGGTTTTACGAAAGAC
CAAGTCAAGGCCATTCATGAATTGAAAAAACCAAAACGTCCTAAAGCGAATAATTTTACAGATATGATGAAACCACCGTC
AACTGCAGGTGAGTTATCGGATTTTACTCGCGATTTGACAGCCATGGCGGAAGCTGGAGCACTCGAAGCAGTTGTTGGTC
GTGACAAAGAAGTCTCTCGCATGGTACAGGTGCTTAGCCGTAAAACCAAGAATAACCCAGTCTTAGTTGGTGATGCTGGT
GTTGGTAAAACTGCCCTAGCTTATGGATTAGCACAACGTATTGCGAGCGGTGAGATTCCTTATGAGTTACGCGACATGCG
CGTTCTTGAATTGGACATGATGAGTGTAGTTGCGGGAACGCGTTTCCGTGGTGACTTTGAAGAGCGTATGAACCAAATTA
TTGATGATATCGAAGCCGATGGTCATATCATTCTTTTTGTGGATGAGATGCATACTATTATGGGTTCTGGTAGTGGTATT
GATAGCACACTTGATGCGGCTAATATCCTAAAGCCTGCTCTTTCTCGTGGAACCCTCCACATGGTTGGGGCTACAACACA
AGAAGAGTACCAAAAACATATTGAAAAAGATGCTGCTCTATCGCGTCGTTTTGCTAAAATTGTTATTGAAGAGCCATCAG
TTGCAGATGCTTTTGAGATTTTGAAAGGATTACGTCCGAGTTATGAAGCCTATCATCATGTGTCACTATCAGATGAAGCT
TTGATGACAGCGGTTAAGTCTGCTCACCGTTATATGACTAGTAAAAACCTGCCTGATTCTGCCATTGATTTGATGGATGA
AGCCAGTGCCACGGTTCAGACCATGGTTAAAAAAGAAGCGCAAGTAGAGTTATCTCCTATTGATGAAGCCCTTTTAGATG
GTGATTTTAAAGCTGTCTCTCGTTTGCTCAAGAAGGAAGAGAAGGTTGCTCTTCCAAAAGTTATCAAGGTAACCGAAGAG
CACATCATGTCTACCCTCAGTCGTCTAACAGGAATTCCTGTGGAAAAAATGACACAGGCTGACAATCAGAAGTATCTCAA
TTTGGAAAAAGAGTTGCATAAGCGTGTGATTGGGCAAGATACGGCGATTTCGGCGATTAGTCGGGCCATTCGTCGTAACC
AGTCGGGTATTAGGACTGGTAAACGTCCTATCGGATCTTTCATGTTCTTGGGGCCAACTGGAGTTGGTAAGACGGAGTTG
GCTAAGGCTTTGGCGGAAGTCCTTTTTGATGATGAATCAGCCCTCATTCGTTTTGACATGTCTGAGTATATGGAAAAATT
TGCCGCCTCACGTCTTAACGGTGCTCCTCCGGGTTATGTCGGCTACGATGAAGGGGGAGAATTAACAGAGAAAGTTCGTC
AGAAACCTTATTCTGTCCTCTTATTTGATGAGGTTGAAAAGGCACATCCAGATATTTTCAATGTTCTTTTGCAAGTGCTG
GATGATGGAATGTTGACGGATAGTCGTGGACGCAAAGTGGATTTTTCAAATACGATTATCATCATGACGTCAAATCTTGG
TGCTACAGCTCTTCGTGATGATAAGACTGTTGGCTTTGGCGTTCAGGATCTCTCACATGACCATGATGCTATGGAAAAAC
GTATTTTGGAAGAGCTTAAAAAAGCTTATCGTCCTGAATTTATCAACCGTATTGATGAGAAGGTTGTCTTCCACAGCTTG
ACACAAGACCATATGAGAGAAGTCGTTAAGATTATGGTTCAACCGTTAATCAAGCAGCTAGCTGAGAAAGGTATTGTCTT
AAAATTCCAACCATCAGCCCTTAAACACTTGGCTGAAGATGGTTACGATATCGAAATGGGAGCTCGCCCACTTCGTCGCA
CCATTCAAACCCAAGTCGAAGACCACCTAGCAGAATTAGTTCTTTCAGGACAATTAGCCACAGGCAATACCCTCAAGATA
GGTGTCAAACAAGGTAAGCTTAAGTTTGATGTGGTTTGA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-50)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-136)

• AAA domain (Cdc48 subfamily) (AAA_2) (542-713)

• ATPase family associated with various cellular activities (AAA) (AAA) (234-366)

• AAA lid domain (AAA_lid_9) (373-441)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (720-799)

3D structure

• AlphaFold DB: A0A2L0D2K7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	71.833	100	0.719
clpC	Streptococcus thermophilus LMG 18311	71.324	100	0.717
clpC	Streptococcus thermophilus LMD-9	71.201	100	0.716
clpC	Streptococcus pneumoniae Rx1	65.56	100	0.656
clpC	Streptococcus pneumoniae TIGR4	65.56	100	0.656
clpC	Streptococcus pneumoniae D39	65.56	100	0.656
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.507	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	44.753	100	0.457