Detailed information NTG0262122

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLG50_RS10915
• Genome accession: NZ_CP025500
• Coordinates: 2218766..2219794 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis subsp. lactis strain G50
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2213766..2224794

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLG50_RS10890 (LLG50_10890)	-	2214053..2214550 (-)	498	WP_103055175.1	nitroreductase family protein	-
LLG50_RS10895 (LLG50_10895)	-	2214537..2214746 (-)	210	WP_003132661.1	hypothetical protein	-
LLG50_RS10900 (LLG50_10900)	-	2214743..2215570 (-)	828	WP_026138971.1	radical SAM protein	-
LLG50_RS11895	-	2215563..2216762 (-)	1200	WP_223247198.1	hypothetical protein	-
LLG50_RS11900	-	2216759..2217685 (-)	927	WP_234818131.1	radical SAM protein	-
LLG50_RS10910 (LLG50_10910)	-	2217788..2218645 (-)	858	WP_103055176.1	Rgg/GadR/MutR family transcriptional regulator	-
LLG50_RS10915 (LLG50_10915)	sepM	2218766..2219794 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
LLG50_RS10920 (LLG50_10920)	coaD	2219781..2220278 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LLG50_RS10925 (LLG50_10925)	rsmD	2220326..2220865 (-)	540	WP_058219570.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLG50_RS10930 (LLG50_10930)	-	2221036..2222256 (-)	1221	WP_103055177.1	MDR family MFS transporter	-
LLG50_RS10935 (LLG50_10935)	lmrP	2222340..2223566 (-)	1227	WP_103055178.1	multidrug efflux MFS transporter LmrP	-
LLG50_RS10940 (LLG50_10940)	-	2223754..2224248 (+)	495	WP_012898649.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=262122 LLG50_RS10915 WP_003132657.1 2218766..2219794(-) (sepM) [Lactococcus lactis subsp. lactis strain G50]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=262122 LLG50_RS10915 WP_003132657.1 2218766..2219794(-) (sepM) [Lactococcus lactis subsp. lactis strain G50]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCGGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGCAAAACAGGAATTGGGA
TTAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCGAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGTGAAATTGCTGGAACTGG
GACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491